Family planning, the ability of females to pick the number, timing, and spacing of their pregnancies, is a fundamental human right and one of the crucial healthcare aspects. In many regions across the world, the autonomy of women in shaping their own lives hinges on the decision of whether and when to go for family planning.  This decision is often affected by awareness and social acceptance of contraception as well as family planning options along with access to affordable hormonal therapies.  However, the focus of many pharmacies has been on ensuring access to safe and modern kinds of contraception and hormone therapy that help improve women’s health. Furthermore, menopausal women may be highly symptomatic today, with disturbing hot flushes and night sweats, yet reluctant to seek medical treatment. To get rid of such problems, Regestrone usage is recommended. Let’s explore the medication benefits below.

About Regestrone tablets

Regestrone 5 mg is similar to the progesterone hormones naturally produced by the body. Your healthcare specialist may offer in 2.5 or 5 mg dosage. Regestrone 5 mg tablet uses include diagnosis or treatment of heavy periods, delay periods, irregular periods, and premenstrual syndrome. The salt norethisterone is used to prepare the Regestrone tablet. It is also effective in preventing pregnancy. It has some side effects, such as abdominal bloating.

Dosage and Administration

Progesterone hormone can be administered differently, including oral, transdermal, injection, rectal, vaginal, sublingual, and intrauterine.

Regestrone 5 mg dosage is used to treat endometriosis, secondary amenorrhea, and abnormal uterine bleeding because of hormonal imbalance in the absence of organic pathology, including submucous fibroids or uterine cancer. The medicine is not recommended to be used with concomitant estrogen treatment in postmenopausal women for endometrial protection

Regestrone must be adapted to the patient’s specific indications and therapeutic response. Sticking to the prescribed dosage and schedule is important for optimal results and to avoid possible side effects.

For amenorrhea and abnormal uterine bleeding due to hormonal imbalance, 2.5 mg to 10 mg may be administered daily for 5 to 10 days.

Progestin (a hormone) withdrawal bleeding usually happens within three to seven days after the discontinuation of Regestrone. Patients with a history of abnormal bleeding may benefit from planned menstrual cycling with Regestrone.

For endometriosis, the initial Regestrone dosage is 5 mg for two weeks. The medicine dosage should be increased by 2.5 mg per day every 14 days until 15 mg per day is achieved. At this level, treatment may be held for six to nine months or until annoying breakthrough bleeding requires temporary termination.


    • Known or suspected pregnancy. There is no indication of Ragstone during pregnancy.
    • Known, suspected, or history of cancer of the breast
    • Undiagnosed vaginal bleeding
    • Blood clotting, or history of blood clotting
    • As a diagnosis test for pregnancy
    • Impaired liver function or liver disease
    • Hypersensitivity to any of the drug components

General Precautions

Because this medicine may cause some degree of fluid retention, which might be influenced by this factor, such as cardiac dysfunction, epilepsy, migraine, or renal dysfunctions, requires close monitoring.

Patients with a history of depression should be carefully monitored, and the medicine should be discontinued if the depression reappears to a serious degree.

In case of undiagnosed vaginal bleeding, appropriate diagnostic measures are indicated.

Research suggests that progestin treatment may have side effects on lipid and carbohydrate metabolism.  The choice of the medicine, its dose, and its regimen may play a significant role in minimizing the side effects. Women suffering from diabetes and hyperlipidemia should be monitored closely during progestin treatment.

Risks associated with Regesterone

Discontinue medication and speak to your health care provider immediately if you develop sudden partial or complete eyesight loss, sudden onset of bulging eyes, complete loss of vision, migraine, or double vision. It is not known if alcohol consumption with this hormone imbalance treatment is safe. While using this hormone therapy for women, it is recommended to perform regular self-breast examinations.  In addition, due to the possibility of photosensitivity, protect yourself from direct sunlight by using sunscreen and protective clothing.

Some warning signs of serious side effects with progestin treatment include dizziness and faintness, breast lumps, changes in speech, chest pain, pains in your legs, changes in vision, shortness of breath, and severe headaches.

Speak to your healthcare specialist immediately if you get any warning signs or other unusual symptoms that cause worry. Common side effects associated with the use of medicine include breast pain, nausea, vomiting, stomach, irregular vaginal bleeding or spotting, hair loss.  Other side effects include fluid retention, liver issues, high blood pressure,  mental depression, vaginal yeast infections, and enlargement of benign tumors of the uterus.

Providing accessible and affordable medicines

Access to affordable hormonal therapy improves women’s health, rights, and economic status worldwide, a fundamental basis for greater quality, education, and prosperity. ensures a continuous supply of contraceptives for those who require them.

Progesterone within compounded bioidentical hormones: clinical safety issues

Progesterone within compounded bioidentical hormone therapy includes creams, tablets, and vaginal preparations.  These do not follow the same regulatory pathways as conventional regulated hormone replacement therapy and have not been scientifically evaluated in research studies for effectiveness and safety against conventional hormone therapy for women. The usage of such compounds is not recommended.

There are concerns associated with the potency, purity, and safety of compounded progesterone products used within compounded bioidentical hormone replacement therapy. There is not enough evidence to suggest that the dosage of progesterone used in compounded formulations offers adequate endometrial protection. Additionally, many such compounded products deliver progesterone in cream or gel formulations. The absorption is variable with fluctuating tissue availability and, as a result, may not offer sufficient endometrial protection.

For the majority of women with unscheduled bleeding on hormone replacement therapy, modifying progestogen intake helps to control bleeding, especially in women who develop unscheduled bleeding in the initial few months after commencing Hormone replacement therapy.

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