Glibenclamide is indicated in type 2 diabetes mellitus. Glibenclamide belongs to the class of sulfonyl ureas and lowers the blood sugar levels by stimulating the insulin production. Diabetes has serious consequences such as kidney damage, blindness and nerve problems. Keeping control over the blood sugar levels of the body decreases the diabetes associated risk.
The ailments it is used for:
Glibenclamide is a prescription medicine used for the treatment of type 2 Diabetes. It is given as an adjunct with diet and exercise in the management of Type 2 diabetes.
Understanding the drug Glibenclamide:
How it works?
Glibenclamide helps in controlling the bloods sugar levels of the body.
It is an oral hypoglycemic drug that stimulates the pancreas to produce more insulin. It acts on the sulfonyl urea receptors present in the pancreas and stimulates the opening of calcium channels. This all leads to more release of insulin.
When should you avoid it?
You should not take Glibenclamide if you:
- Have any allergy to the active ingredient present in it
- Are allergic to sulfonyl urea or sulfonamides
- Have diabetic ketoacidosis
- Have jaundice
- Have serious kidney infection
- Have liver related problems
- Are having type 1 diabetes
- are pregnant or planning to become a pregnant
- are breast feeding
How much to take?
One cannot fix the dose for type 2 diabetes mellitus. It varies from person to person. Before recommending a dose to a patient, various factors are considered like health status, body’s weight and age. Doctor will recommend the best suitable dose for you. Usual prescribed initial dose is 5 mg daily. It can be increased or decreased depending upon the response and the condition.
What are the strengths available?
Glibenclamide is available in one strength combination on our website:
- Glybuvin 5 mg
- Semi Daonil 2.5 mg
Who is the manufacturer?
Glybuvin is manufactured by Sun Pharma, a pharmaceutical giant and is available on our website in the pack of 30 tablets.
Semi Daonil is manufactured by Sun Pharma, a pharmaceutical giant and is available on our website in the pack of 30 tablets.
How to take?
Glibenclamide is taken exactly as prescribed by your doctor. Take the tablet with full glass of water. Don’t crush or chew the tablet.
When to take?
Take the medicine with first meal of the day (breakfast) as instructed by your doctor, once daily. In case of higher doses, drug is given twice a day. The intake of dosage depends upon your condition. Always take the medicine as per prescription.
For how long should it be taken?
This drug is meant to be taken on regular basis, so keep on taking the drug as long as recommended by the Doctor. Sudden discontinuation can lead to undesired and severe conditions.
What if you take too much (overdose)?
If overdose, immediately consult with your concerned doctor. Take medical help as soon as possible if you encounter below stated symptoms:
- Rapid and fast heartbeat
What if you miss the dose?
Try to take the medicine at the same time each day; this reduces the chances of missing dose. Talk to your Doctor if you miss the Dose. Don’t double up the dose in order to compensate with the previous one.
What are the side effects?
Every medicine possesses some side effects, same way this drug also have some undesired effects with it. Glibenclamide shows common and serious side effects such as:
- increased or decreased appetite
- more frequent urination
- abdominal discomfort and pain
- Skin becomes sensitive to Sun
Some serious and rare side effects that need serious consideration are stated below:
- Hypoglycemic effects like restlessness, confusion, blurred vision, slurred speech, low blood pressure, fatigue drowsiness, anxiety and confusion
- Abdominal cramps
- Swelling in throat and face
- Rapid pulse
Are there any possible drug interactions?
Always inform your doctor about the drugs you are taking till date. Give a complete list of prescription or non prescription drugs and any other disease conditions. This way, doctor is able to decide and give you the list of drugs and other things that may interact with Glibenclamide. The drugs that may interact with Glibenclamide are as follows:
- Other drugs having same ingredients
- Enalapril, Ramipril
- Para amino salicylic acid
What are the things to be taken care of?
- Always take the medicine as per prescription
- Don’t use the expired drug
- Always monitor your blood sugar levels
- Glibenclamide makes the skin sun sensitive so use sunscreen creams in order to avoid tanning or pigmentation
- Avoid consumption of alcohol while using this drug
- Don’t share your medicine with anybody, even if they have the same symptoms
- Follow strict diet and exercise regimen while taking this drug
- Always store the medicine at the room temperature and away from moisture, heat and light
- Keep a complete record of all the medicines you are taking along with this medicine