Emeset 4mg
| Pack Size | Qty | Price Per Pill or Unit | Price | Offer | ||
|---|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.43 | US$ 12.76 |
|
|||
|
||||||
| 60 Tablet/s | US$ 0.43 | US$ 25.54 |
|
|||
|
||||||
| 90 Tablet/s | US$ 0.43 | US$ 38.32 |
|
|||
|
||||||
Description
| SKU | 768 |
|---|---|
| Generic For | Zofran |
| Strength | 4mg |
| Active Ingredient | Ondansetron |
Emeset 4mg for Nausea And Vomiting — Trusted Generic Zofran
Emeset 4mg is an antiemetic medication containing ondansetron as its active ingredient. It is used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, and surgery.
What is Emeset 4mg?
Emeset 4mg is a prescription antiemetic tablet containing 4mg of ondansetron hydrochloride. Ondansetron is one of the most widely used and clinically validated antiemetic agents worldwide, classified as a selective serotonin 5-HT3 receptor antagonist. It is used to prevent and treat nausea and vomiting associated with highly emetogenic chemotherapy, moderately emetogenic chemotherapy, radiation therapy, and postoperative nausea and vomiting (PONV). Emeset 4mg is particularly effective in preventing acute nausea and vomiting and is a first-line antiemetic in oncology settings.
Manufacturing details: Emeset 4 mg is manufactured by Cipla Ltd. under strict GMP guidelines. The formulation contains ondansetron and undergoes rigorous quality testing, standardised production processes, and regulatory compliance to ensure safety, effectiveness, and consistent pharmaceutical quality.
The active ingredient & their mechanism?
Nausea and vomiting triggered by chemotherapy, radiotherapy, and surgery are primarily mediated by serotonin (5-hydroxytryptamine, 5-HT) released from enterochromaffin cells in the small intestine, which activates 5-HT3 receptors on vagal afferent neurons. These neurons transmit signals to the vomiting centre in the brain (nucleus tractus solitarius and the area postrema). Ondansetron selectively and competitively blocks 5-HT3 receptors in both the gastrointestinal tract and the central chemoreceptor trigger zone (CTZ). By blocking serotonin-mediated stimulation at these sites, ondansetron effectively prevents and reduces nausea and vomiting.
Clinical uses
- Prevention of nausea and vomiting associated with highly and moderately emetogenic chemotherapy
- Prevention and treatment of radiation-induced nausea and vomiting (RINV)
- Prevention and treatment of postoperative nausea and vomiting (PONV)
- Nausea and vomiting in pregnancy (hyperemesis gravidarum) — under medical supervision
- Nausea and vomiting in gastroenteritis (acute use)
- Cyclical vomiting syndrome (adjunct management)
Brand vs generic differences
Emeset 4mg is the generic equivalent of Zofran 4mg. Both contain ondansetron 4mg and are bioequivalent in terms of absorption, efficacy, and safety. Cipla Ltd. is one of the world's foremost generic pharmaceutical manufacturers, with products approved across multiple international markets, including the USA (FDA), the UK (MHRA), and the WHO. Choosing Emeset 4mg over branded Zofran offers significant cost savings — particularly important for oncology patients who may be taking ondansetron for months during chemotherapy.
Alternative medicines & strengths on ReliableRxPharmacy: ReliableRxPharmacy also stocks Emeset 8mg for patients requiring the higher dose regimen.
Key benefits
- Highly effective prevention of chemotherapy-induced nausea and vomiting (CINV)
- Well-tolerated with no sedation — unlike older antiemetics (e.g. metoclopramide, phenothiazines)
- No risk of extrapyramidal side effects associated with dopamine antagonist antiemetics
- Available in multiple formulations (tablet, oral dissolving tablet, injection) for flexible use
- Rapid onset of action when taken 30 minutes before chemotherapy or surgery
- Generic manufacturing by Cipla ensures quality at an affordable price
- Can be combined with other antiemetics (corticosteroids, NK1 antagonists) for enhanced efficacy
Dosage & administration of ondansetron tablets
For chemotherapy-induced nausea and vomiting, the typical adult dose is 8mg (two Emeset 4mg or Zofran tablets) taken 30 minutes before chemotherapy, followed by 8mg 4–8 hours later, then 8mg twice daily for 1–2 days post-chemotherapy. For postoperative nausea and vomiting, a single 4mg or 8mg dose given 1 hour before surgery or immediately after anaesthetic induction is standard. Tablets should be swallowed whole with water. They may be taken with or without food. Store below 30°C away from light and moisture. An oral dissolving tablet form is available for patients with difficulty swallowing.
Precautions, warnings & drug interactions related to ondansetron tablets
Emeset 4mg or Zofran should not be used in patients with known hypersensitivity to ondansetron or other 5-HT3 antagonists. QT interval prolongation is a class effect of 5-HT3 antagonists; ondansetron should be used with caution in patients with existing QT prolongation, cardiac arrhythmias, or those taking other QT-prolonging medicines such as antiarrhythmics, antipsychotics, and fluoroquinolone antibiotics. Congenital long QT syndrome is a contraindication. Dose adjustment is recommended in patients with severe hepatic impairment. Concurrent use with apomorphine (for Parkinson's disease) is contraindicated due to the risk of severe hypotension. Caution with tramadol (possible reduced pain-relief efficacy via shared serotonin pathway interactions).
Side effects of ondansetron tablets
Emeset 4mg or Zofran is generally very well tolerated. The most commonly reported side effects are headache and constipation, which affect a significant proportion of patients. Flushing and warmth are occasionally noted. Diarrhoea and dizziness are less common. Transient asymptomatic elevations of liver enzyme levels have been reported, typically resolving without intervention. Serious but rare adverse effects include QT interval prolongation and cardiac arrhythmias (including Torsades de Pointes), severe allergic reactions (anaphylaxis, urticaria, angio-oedema), and serotonin syndrome when combined with other serotonergic agents. Patients taking multiple serotonergic medications should be monitored closely. If enough nausea and vomiting happen, do contact your healthcare professional straight away.
Benefits of buying this medicine online from ReliableRxPharmacy
Buying Emeset 4mg from ReliableRxPharmacy is particularly valuable for cancer patients undergoing chemotherapy who require an ongoing supply of antiemetics. The cost savings compared to branded Zofran can be substantial over a full course of chemotherapy. ReliableRxPharmacy ships discreetly and reliably worldwide, with tracked delivery to the USA, UK, Canada, Australia, and beyond. All Cipla products sourced by ReliableRxPharmacy meet international quality standards, providing patients and carers with confidence in the antiemetic efficacy of every tablet. The platform's responsive customer support is available to assist with any order-related queries.
20% OFF
Terms and Conditions Apply*
Flat 20% OFF
on your first purchase
20% off only on the product value
Maximum discount value $20
Only one coupon can be used at a time
Coupon code will be mailed on
your registered email address.
Login
Sign up
Flat 20% OFF
on your first purchase
20% off only on the product value
Maximum discount value $20
Only one coupon can be used at a time
Coupon code will be mailed on
your registered email address.
Login
Sign Up
Flat 20% OFF
on your first purchase
20% off only on the product value
Maximum discount value $20
Only one coupon can be used at a time
Coupon code will be mailed on
your registered email address.
Forgot Password ?