| Pack Size | Qty | Price Per Pill or Unit | Price | Offer | ||
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| 30 Tablet/s | US$ 1.83 | US$ 55.0043%US$ 96.10 |
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| 60 Tablet/s | US$ 1.67 | US$ 100.0048%US$ 192.19 |
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| 90 Tablet/s | US$ 1.56 | US$ 140.0064%US$ 384.38 |
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Description
| SKU | 49 |
|---|---|
| Generic For | Augmentin |
| Strength | 1000mg (875+125) |
| Manufacturer | GSK, India |
| Active Ingredient | Amoxicillin Clavulanic Acid |
Augmentin Duo for Bacterial Infections — Order Online
Augmentin 1000mg (875mg/125mg) is the highest strength oral antibiotic formulation in the Augmentin range and is indicated for the treatment of severe and complex bacterial infections. Containing Amoxicillin 875mg combined with clavulanic acid 125mg, this powerful antibiotic combination is a prescription medicine. It is commonly prescribed when lower-strength formulations are insufficient to fully control a more serious infection.
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What is Augmentin 1000mg (875/125mg)?
Augmentin 1000mg refers to the total active ingredient content per tablet — 875mg of amoxicillin and 125mg of clavulanic acid. This formulation is designed for twice-daily administration, allowing a high total daily amoxicillin dose while keeping clavulanic acid exposure at a level that minimises gastrointestinal side effects. It offers a potent, broad-spectrum antibacterial effect suitable for adults and children over 12 years dealing with severe infections.
Active Ingredients & how do they work?
Amoxicillin (875mg): At this high dose, amoxicillin provides intensive bactericidal action. It disrupts bacterial cell wall synthesis by irreversibly binding to penicillin-binding proteins, leading to rapid lysis and death of susceptible bacteria. The 875mg dose ensures high drug concentrations in the blood and tissues, making it appropriate for more severe or deeper infections.
Clavulanic acid (125mg): Even at the highest amoxicillin dose level, the 125mg clavulanic acid component remains consistent. By inhibiting beta-lactamase enzymes produced by resistant bacteria, it extends the spectrum of amoxicillin to cover organisms that would otherwise be untreatable with a penicillin-class antibiotic alone.
Clinical uses of amoxicillin
Augmentin 875/125mg is indicated for severe bacterial infections, including:
   -  Community-acquired pneumonia — particularly moderate-to-severe cases
   -  Acute bacterial sinusitis — when a high-dose, short-course approach is    -  preferred
   -  Complicated urinary tract infections — including pyelonephritis
   -  Complicated skin and soft tissue infections — deep cellulitis, infected surgical wounds
   -  Diabetic foot infections (mild-to-moderate) — under specialist supervision
   -  Bite wounds — animal or human bites with high infection risk
   -  Severe dental infections and oral abscesses
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Key benefits of Augmentin 1000mg
   -  Highest-strength oral Augmentin formulation — suitable for severe infections
   -  Twice-daily dosing improves patient convenience and adherence versus three-times-daily regimens.
   -   A consistent clavulanic acid dose (125mg) limits unnecessary side effects while maintaining resistance coverage.
   -  Equivalent efficacy to some IV antibiotic regimens in appropriate patients, avoiding hospitalisation
   -  Effective against a very broad spectrum of bacteria, including resistant strains
   -  Widely recognised formulation with extensive worldwide clinical evidence
Dosage, administration & storage of amoxicillin/clavulanic acid
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Dosage: The standard adult dose is one 875/125mg tablet twice daily (every 12 hours). Some protocols specify three times daily; follow your doctor's precise instructions. Typical treatment duration ranges from 5 to 14 days, depending on the type and severity of the infection.
Administration: Take at the beginning of a meal to enhance clavulanic acid absorption and reduce gastrointestinal side effects. Swallow the tablet whole with a full glass of water. Do not crush or chew extended-release versions. Complete the entire prescribed course.
Storage: Store below 25°C in a cool, dry, dark location. Keep the packaging sealed and away from moisture. Store out of reach of children and discard any unused tablets responsibly after the expiry date.
Related strengths & products: Augmentin 1000 mg (amoxicillin 875 mg with clavulanic acid 125 mg) is part of a broader range of strengths and formulations designed for different infection severities. Related options include Augmentin 375 mg, Augmentin 625 Duo and pediatric suspensions such as Augmentin Dry Syrup 30ml. These alternatives allow flexible dosing and may be prescribed based on the patient's age, disease severity, and treatment response.
Precautions, warnings & drug interactions with amoxicillin/clavulanic acid
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This is the highest-strength oral Augmentin formulation, and precautions should be observed. Do not use if you have a penicillin or beta-lactam allergy. Use with caution in patients with significant renal or hepatic impairment — dose reduction may be necessary.
Drug interactions of particular note:
   -  Warfarin/anticoagulants — significant interaction; regular coagulation monitoring required
   -  Methotrexate — Amoxicillin reduces renal clearance; monitor for methotrexate toxicity
   -  Probenecid — delays amoxicillin renal excretion, increasing plasma concentrations
   -  Allopurinol — increased risk of rash when combined with amoxicillin
   -  Oral contraceptives — reduced effectiveness; use additional contraceptive precautions
   -  Mycophenolate mofetil (immunosuppressant) — may reduce its efficacy
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In patients with renal impairment (creatinine clearance <30 mL/min), this strength is generally not recommended. Your doctor will advise on appropriate alternatives.
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Side effects of amoxycillin/clavulanic acid
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As with all Augmentin formulations, gastrointestinal side effects are most common. At the 875/125mg strength, the clavulanic acid dose remains the same as in lower-strength formulations, which helps limit digestive side effects relative to the total antibiotic dose. Common side effects: diarrhoea, nausea, vomiting, indigestion or abdominal discomfort, headache, and skin rash (mild). Serious side effects requiring immediate medical attention:
   -  Severe allergic reactions (anaphylaxis) — seek emergency care
   -  Jaundice or liver dysfunction — dark urine, yellowing of skin or eyes
   -  Severe prolonged diarrhoea — may indicate Clostridioides difficile colitis
   -  Severe skin reactions — blistering, peeling, or widespread rash
Benefits of buying Augmentin online
   -  Significantly lower prices than retail pharmacies for this premium-strength antibiotic online.
   -  Free worldwide shipping on qualifying orders
   -  Convenient home delivery — especially beneficial for patients recovering from infection
   -  Secure, discreet packaging ensuring privacy
   -  Great deals and discounts on genuine medicines at ReliableRxPharmacy
   -  Access to the complete Augmentin strength range in one trusted online store.
   -  Fast order processing with reliable delivery tracking.
   -  Verified customer reviews for added purchasing confidence.
Why is this called both Augmentin 1000mg and Augmentin 875/125mg?
The total weight of active ingredients per tablet is approximately 1000mg (875mg amoxicillin + 125mg clavulanic acid = 1000mg), which is why it is often referred to as Augmentin 1000mg. However, the precise composition is 875mg/125mg.
Is Augmentin 875/125mg stronger than Augmentin 500/125mg?
Yes. Augmentin 875/125mg contains significantly more amoxicillin (875mg vs 500mg). This higher dose provides more intensive bactericidal activity and is prescribed for more severe or treatment-resistant infections.
How is the twice-daily Augmentin 875/125mg dosing beneficial?
Twice-daily dosing is more convenient for patients and may improve adherence compared to three-times-daily regimens. The high individual dose of 875mg amoxicillin maintains effective drug levels throughout each 12-hour dosing interval.
Can Augmentin 875/125mg be used for pneumonia?
Yes. Augmentin 875/125mg is a commonly prescribed oral antibiotic for community-acquired pneumonia in adults. However, the decision to treat at home with oral antibiotics versus hospitalisation depends on the severity of the pneumonia and your overall health status.
What should I do if I develop a rash while taking Augmentin 875/125mg?
A mild rash may be a common side effect, but any rash could indicate an allergic reaction. Stop the medication and contact your doctor immediately.
Is this formulation safe for patients with kidney disease?
Patients with significant renal impairment (creatinine clearance below 30 mL/min) should not use the 875/125mg formulation. Those with moderate kidney impairment should use a lower-strength formulation with an adjusted dosing frequency.
Can Augmentin 875/125mg be cut or crushed?
Standard immediate-release tablets may be broken in half if needed, but should not be crushed without medical advice. Extended-release (XR) versions should never be crushed or chewed.
What happens if I do not complete the full Augmentin course?
Stopping the course early is one of the primary drivers of antibiotic resistance. Even if symptoms improve within the first few days, some bacteria may remain.
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