| Pack Size | Qty | Price Per Pill or Unit | Price | Offer | ||
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| 30 Tablet/s | US$ 0.67 | US$ 20.00 |
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| 60 Tablet/s | US$ 0.58 | US$ 35.00 |
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| 90 Tablet/s | US$ 0.56 | US$ 50.00 |
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Description
| SKU | 1013 |
|---|---|
| Generic For | Janumet |
| Strength | 50+1000mg |
| Active Ingredient | Sitagliptin+ Metformin |
| Marketed By | Sun Pharma, India |
Istamet 50+1000mg for Diabetes Management — Trusted Generic Janumet
Sitagliptin and Metformin HCL are the active ingredients in Istamet 50+1000mg. It is an anti-hyperglycemic or anti-diabetic drug that contains DPP-4 inhibitors and is administered orally to help reduce blood sugar.
Sitagliptin works by reducing high blood glucose levels. These drugs increase the secretion of insulin and decrease the release of glucagon by the pancreas. This keeps the blood glucose levels at normal levels. When the blood glucose levels become normal, the increased glucagon and insulin changes stop, preventing hypoglycemic situations.
Metformin Hcl is an anti-hyperglycemic agent that decreases glucose production from the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing glucose uptake and utilization.
The medicine comes in tablet form and has various strengths, including Istamet 50+500 mg and Istamet 50+1000mg tablets. Sun Pharma, India, manufactures this medicine.
What is Janumet?
The combination of Sitagliptin and Metformin HCL is sold under Janumet, among others. The working efficacy of Janumet and Istamet is similar in treating type 2 diabetes mellitus; however, Istamet 50+1000mg tablets price and packaging may vary from Janument.
Where to order Istamet 50+1000mg tablets?
You can buy Istamet 50+1000mg tablets online and from a medical store. To save the best on medicine, buy Istamet online from Reliablerxpharamcy for doorstep delivery.
How to take the Sitagliptin and Metformin combination pill?
Janument or Istamet 50+1000mg tablet uses - You should take this medicine regularly as your doctor prescribes. Follow the directions carefully to achieve the desired results. The anti-diabetic agent works best when used along with diet and regular exercise.
Your dose will depend on your condition, blood glucose levels, and other medicines you take, including vitamins or herbal supplements. Taking it with meals helps to reduce the chances of an upset stomach.
This medicine is available in the form of a tablet. Swallow the tablet with a glass of water, and do not chew, break or crush it. It is important to take the drug at the same time every day; doing this helps that you do not forget to take medicine. If you miss taking a dose, skip the missed dose and take the next dosage at the scheduled time. Do not take two doses to make up for the missed one.
An overdose of the medicine may lead to harmful side effects, which may lead to hypoglycemia. If this is the case, you may need urgent medical help. Consult your doctor immediately if you face any of the symptoms like back, muscle, or joint pain, abdominal pain, nausea, headache, osteoarthritis, diarrhea, constipation, dizziness etc.
Take the medicine for as long as your doctor has prescribed it. This medicine helps control diabetes but does not cure it, so if you have any doubt about it, do not hesitate to speak to your doctor.
Warning and precautions with Sitagliptin and Metformin combination pill
Before taking the Janument or Istamet 50/1000 mg, tell your doctor if you are allergic to Sitagliptin, metformin, or other medicine ingredients. Before you consider an anti-diabetic agent, your doctor should know your medical history, especially of liver disease, severe breathing problems, kidney disease, stones in your gallbladder, and a disease of the pancreas, your pregnancy status, or if you are a breastfeeding baby. Limit alcohol while receiving Sitagliptin/metformin formulation because it can increase your risk of developing low blood sugar, disease of the pancreas, or lactic acidosis. High fever, water pills, diarrhea, vomiting, or too much sweating may cause dehydration and increase your risk of lactic acidosis.
Drugs that can interact with this medicine include probenecid, ivacaftor, non-steroidal anti-inflammatory drugs, sulfa drugs, aspirin or other salicylates, beta-blockers, and monoamine oxidase inhibitors.
Store the medicine in a cool and dry place. Keep it out of the reach of pets and children. Also, keep it away from heat and humidity. Never use medicines that have crossed the expiry date.
Side effects of Sitagliptin and Metformin combination pill
Along with its needed effects, Janument or Istamet 50+1000mg tablet side effects may cause some unwanted effects. Although not everyone experiences side effects, seek medical attention if any side effects become bothersome.
You may experience unusual tiredness, dizziness, blurred vision, headache and drowsiness, fast heart rate, or low blood glucose levels. Avoid driving or indulging in activities that require you to be attentive. More common side effects include indigestion, lack of strength, feeling of fullness, and gas in the stomach.
If you experience any of the symptoms, get medical help.
What is Istamet 50+1000mg used for?
Istamet 50+1000mg is used to treat type 2 diabetes [a condition where your body cannot control blood sugar levels properly]. It contains two medicines: sitagliptin, which helps your pancreas release more insulin [a hormone that lowers blood sugar], and metformin, which reduces the amount of sugar your liver makes and helps your body use insulin better. Your doctor prescribes this combination when diet and exercise alone don't adequately control your blood sugar. You take it by mouth alongside a healthy diet and regular physical activity.
Who is Istamet 50+1000mg meant for, and is it right for me?
Istamet 50+1000mg is prescribed for adults with type 2 diabetes (high blood sugar caused when your body doesn't use insulin properly). Your doctor may suggest it if diet and exercise alone haven't controlled your blood sugar, or if you're already taking one of these medicines separately. It combines two medicines that work together to lower blood sugar levels. Whether it's right for you depends on your diabetes history, other health conditions, kidney function, and current medicines. Only your doctor can decide if this tablet suits your individual situation. Never start or stop it without consulting them.
How long should I keep using Istamet 50+1000mg?
Istamet is a long-term medicine for managing type 2 diabetes. You should continue taking it as long as your doctor recommends, which is usually indefinitely unless your blood sugar control improves significantly or your doctor advises otherwise. Do not stop taking Istamet without consulting your doctor, even if you feel better, as this can cause your blood sugar to rise again. Your doctor will review your treatment regularly and may adjust your dose or change your medicine if needed based on your blood sugar levels and overall health.
Should I take Istamet 50+1000mg with food, and does the time of day matter?
You can take Istamet with or without food — food does not affect how the medicine works. However, taking it with meals may help reduce stomach upset if you experience any digestive discomfort. The time of day does not matter, but try to take your doses at the same times each day to help you remember. Follow your doctor's instructions about how many tablets to take and when.
What things can affect how well Istamet 50+1000mg works?
Several things can affect how well Istamet works for you. Alcohol consumption, especially heavy drinking, can lower your blood sugar too much. Certain medicines, including some diuretics (water pills) and steroids, may reduce its effectiveness. Kidney or liver problems can affect how your body processes the medication. Dehydration and severe illness also impact its performance. Diet plays a role—eating high-sugar or high-fat foods regularly reduces benefits. Stress and lack of physical activity can worsen blood sugar control. Always tell your doctor about other medicines you take and any health conditions you have.
How quickly will I notice Istamet 50+1000mg working?
Istamet starts working immediately after you take it, but you won't feel sudden changes. Most people notice improved blood sugar control within 1–2 weeks of regular use, though the full effect takes 2–3 weeks. Your doctor will check your blood sugar levels with blood tests to confirm it's working properly. Take it exactly as prescribed every day for best results.
Are there any serious warning signs I should watch out for with Istamet 50+1000mg?
Watch for signs of lactic acidosis (a serious buildup of acid in your blood): severe nausea, vomiting, stomach pain, rapid or difficult breathing, or unusual muscle pain. Seek immediate medical help if you experience these. Also watch for severe hypoglycaemia (very low blood sugar): confusion, sweating, trembling, or loss of consciousness. Report any signs of pancreatitis (pancreas inflammation): severe upper stomach pain, back pain, or persistent vomiting. Contact your doctor immediately if you notice severe allergic reactions: rash, swelling, or breathing difficulty. Tell your doctor right away about any new or worsening symptoms.
Is it safe to use Istamet 50+1000mg for a long period of time?
Yes, Istamet is generally safe for long-term use when taken as prescribed by your doctor. Both sitagliptin (a medicine that helps your pancreas release insulin) and metformin (a medicine that reduces blood sugar) have been used safely for many years to manage type 2 diabetes. However, your doctor should monitor your kidney function and blood sugar levels regularly with blood tests. Long-term safety depends on taking it exactly as directed and attending all scheduled check-ups. Never stop or change your dose without consulting your doctor first.
Are there any foods or drinks I should avoid while on Istamet 50+1000mg?
You can eat most foods normally while taking Istamet 50+1000mg. However, limit alcohol, as it may increase the risk of lactic acidosis (a serious condition where acid builds up in your blood). Avoid high-sugar foods and drinks—they work against your medicine's purpose of controlling blood sugar. Eat regular, balanced meals to help stabilize your blood sugar levels. If you have questions about specific foods or your diet, ask your doctor or pharmacist for guidance.
Can I use Istamet 50+1000mg alongside my other medicines or supplements?
Istamet 50+1000mg can interact with some medicines and supplements, so you must tell your doctor about everything you're currently taking before starting it. Certain drugs—like some blood pressure medicines, diuretics (water tablets), and NSAIDs (pain relievers)—may affect how your body handles metformin. Some supplements can also interfere. Your doctor or pharmacist will check for unsafe combinations and adjust your treatment if needed. Never stop or change any medicine without medical advice.
Are there any groups of people who should be extra careful when using Istamet 50+1000mg?
Certain groups need extra caution with Istamet. If you have kidney problems, liver disease, or heart failure, tell your doctor before using this medicine. Pregnant or breastfeeding women should not use Istamet without medical advice. People with a history of pancreatitis (inflammation of the pancreas) need careful monitoring. If you're scheduled for surgery or imaging with contrast dye, inform your healthcare provider. Older adults may need dose adjustments. Always discuss your full medical history with your doctor before starting Istamet.
Do I need a different dose of Istamet 50+1000mg if I have kidney or liver problems?
Your kidney and liver function directly affect how your body processes Istamet. If you have kidney problems, your doctor may need to lower your dose or monitor you more closely, because metformin (one ingredient) can build up in your blood if your kidneys don't work well. Liver problems may also require dose adjustment. Never change your dose yourself—always tell your doctor about any kidney or liver issues before taking this medicine, and follow their guidance on your specific dose.
What are my options if Istamet 50+1000mg does not agree with me?
If Istamet 50+1000mg does not agree with you, speak to your doctor or pharmacist. They may suggest taking it with food, adjusting the timing of doses, or reducing the dose temporarily. Your doctor might also switch you to a different strength of Istamet or recommend an alternative diabetes medicine altogether. Do not stop taking this medicine without medical advice, as this could affect your blood sugar control. Your healthcare team can find the best option for your situation.
Which strength of Istamet 50+1000mg is most commonly recommended?
Istamet 50+1000mg is the strength you're asking about — and it's one of the most commonly prescribed combinations. This tablet contains 50mg of sitagliptin (a medicine that helps your pancreas release insulin) and 1000mg of metformin (a medicine that helps your body use insulin better). Your doctor chooses this strength based on your blood sugar levels and how your body responds to treatment. The right dose for you depends on your individual needs, so always take exactly what your doctor prescribes.
How quickly can I receive Istamet 50+1000mg if I order from ReliableRxPharmacy?
Your Istamet 50+1000mg order will arrive within 20–30 business days. ReliableRxPharmacy sources this medicine from authorised distributors of the manufacturers and ships to addresses worldwide. Delivery times apply to both standard international and North America orders. Once your order is processed, you'll receive tracking information so you can monitor your package's progress until it reaches you.
Is it safe to buy Istamet 50+1000mg online, and how do I know it is genuine?
Yes, it's safe to buy Istamet 50+1000mg online from licensed pharmacies like ReliableRxPharmacy.com. We source all medicines, including Istamet, from authorised distributors of manufacturers, ensuring genuine products. To ensure you are purchasing genuine medication, choose a trusted pharmacy that follows legal pharmacy practices and obtains medicines from authorised distributors. Review the pharmacy’s contact details, ordering policies, and customer feedback before placing an order. Be cautious of websites advertising prescription medicines at unrealistically low prices or making exaggerated claims. A reputable pharmacy will follow appropriate prescription requirements and maintain transparent standards for dispensing medications safely and responsibly.
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