|Price Per Pill or Unit
|US Brand Name
|150 + 300 mg
|Lamivudine + Zidovudine
Duovir 150/300 mg is a combination drug of antiviral medicines, also known as antiretrovirals. It contains three active ingredients, namely lamivudine, zidovudine and nevirapine, belonging to the following two groups nucleoside analogues (lamivudine and zidovudine) and non-nucleoside reverse transcriptase inhibitors (nevirapine). These drugs are prescribed for the treatment of Human immunodeficiency virus (HIV) infection. Doctors prescribe Duovir N combination therapy for the treatment of HIV infection. Treatment with this triple combination will only be instituted by your doctor when you are stable on the three individual pharmaceutical agents. The antiretroviral agents reduce the amount of HIV in your body and keep it at a low level. It is also known to increase CD4 (type of white blood cell) counts. These white blood cells play a key role in maintaining a healthy immune system to help fight infections. Response of the treatment is different in different people. Your doctor will be monitoring the effectiveness of your treatment.
You should check with your doctor the recommended dose for Duovir N and carefully follow the instructions given o your prescription. The recommended dose in adults and children with a 25 kg or more bodyweight is one tablet twice daily. The doctor can make appropriate dose reductions as per the treatment response.
Before starting Duovir 150/300 mg, tell your doctor about all your medical conditions, including problems with your liver, rash, or undergoing dialysis. Your doctor should also be aware of your pregnancy status; if you are pregnant, planning to become pregnant, or are breastfeeding.
Nevirapine, one of Duovir 150 300 mg active components, may change the effect of other medicines, and other medicines can affect the mode of action of nevirapine. Inform your doctor about all the medicines you take, including over the counter drugs, vitamins, and herbal supplements. Do not take rifampin or ketoconazole with Nevirapine. You should tell your doctor if you take rifabutin, clarithromycin, and fluconazole. The antiretroviral may not be right for you or may need close monitoring of your health condition. It is advised not to take products containing ST. John’s wort, which can reduce the amount of nevirapine in the bloodstream. If you take contraceptive pills, you should not completely rely on them to prevent unwanted pregnancy. Your birth control pills may fail to function if you take medicine containing nevirapine. Therefore, it is important to discuss with your doctor other types of birth control methods.
Duovir can cause serious liver damage and skin reactions, and skin reactions that can cause life-threatening effects. Any patient can experience such side effects, but some patients are at high risk than others. Other common side effects of nevirapine include fever, nausea, headache, vomiting, fatigue, diarrhoea, abdominal pain, and myalgia. Changes in body fat have also been reported in some patients taking this antiretroviral agent. The changes may include increased fat in the breast, upper back and neck, around the trunk.