Nizonide DT 200 mg containing Nitazoxanide is a new thiazolide antiparasitic agent that shows an excellent efficacy against a wide variety of protozoa and helminths. It is available for oral administration and is well tolerated, with primarily mild gastrointestinal side effects. Originally developed as an antiprotozoal agent, Nitazoxanide was later identified as a broad-spectrum antiviral drug used to treat influenza. It is safe and well-tolerated in both adults and children. The tablet formulation is given to immunocompetent adults and adolescents to treat diarrhoea caused by Giardia lamblia or Cryptosporidium parvum.

Nizonide is effective in treating Giardia intestinalis- induced diarrhea in patients. It is available in the form of a dispersible tablet that one needs to take with food. Continue to take medicine for the time being prescribed to you, even if symptoms disappear after a few doses. Sudden discontinuation may result in the return of the infection.  Inform your doctor if your condition lasts or get worse. Follow all directions given on the prescription. Tell your doctor about all your medical conditions, allergies, and all medicines you use. To make sure Nitazoxanide is safe for you, tell your doctor if you have a liver disorder, kidney disease, HIV, or a weak immune system.

Nizonide dispersible tablets are contraindicated in patients with a prior hypersensitivity to Nitazoxanide or any other ingredients in the formulation. The effectiveness of this antiprotozoal agent in patients with impaired hepatic or renal function has not been studied. Therefore, it should be used with caution in patients with liver or kidney disorders.

The medicine has not been studied to treat diarrhea caused by giardia lamblia in HIV infected or immunocompetent patients.

The tablet form of the medicine should not be given to a child younger than 12 years old. For children aged 1 to 11 years, Nitazoxanide is available in the form of oral suspension. Antiprotozoal medicine is not expected to be harmful to an unborn baby. Let your doctor know if you are pregnant. It is not known whether the drug is excreted in breast milk. Because many pharmaceutical agents are excreted in human milk, therefore caution should be exercised when the medication is given to a nursing woman.

The most common adverse effects of Nizonide DR 200 mg were nausea, diarrhea, headache, and abdominal pain. In clinical trials, HIV infected patients aged 12 years and older who received Nitazoxanide tablets for the treatment of diarrhea, some patients were asked to discontinue therapy because of a side effect.

Check out for the following side effects:

• Nervous system: insomnia, dizziness, hypesthesia, dizziness, tiredness.
• Respiratory system: lung disease, epistaxis, pharyngitis
• Digestive system: dry mouth, anorexia, vomiting, thirst, dyspepsia, constipation,
• Skin- rash, pruritus
• Cardiovascular system: hypertension, syncope, tachycardia
• Urogenital system: Dysuria, metrorrhagia, edema labia, amenorrhea, discolored urine, kidney pain
• Muscular system: leg cramps, myalgia, spontaneous bone fraction.