| Pack Size | Qty | Price Per Pill or Unit | Price | Offer | ||
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| 30 Tablet/s | US$ 0.65 | US$ 19.50 |
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| 60 Tablet/s | US$ 0.65 | US$ 39.00 |
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| 90 Tablet/s | US$ 0.65 | US$ 58.50 |
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Description
| SKU | 1014 |
|---|---|
| Generic For | Janumet |
| Strength | 50 + 500 mg |
| Manufacturer | Sun Pharma, India |
| Active Ingredient | Sitagliptin+ Metformin |
Istamet 50 + 500 mg for Diabetes Management — Trusted Generic Janumet
Istamet 50 + 500 mg comprising two active ingredients: Sitagliptin Phosphate and Metformin HCl. Together, they improve the blood glucose levels of type 2 diabetes patients. This drug is administered along with diet and exercise and helps lower the body's blood sugar levels.
The working mechanism of the drug
Sitagliptin Phosphate and Metformin HCl help lower the body's blood sugar levels.
Sitagliptin Phosphate - Sitagliptin is a dipeptidyl peptidase 4 inhibitor. It works by increasing the release of the Incretin hormone, which raises insulin levels. This, in turn, lowers glucose production and maintains appropriate blood glucose levels in the body.
Metformin HCl - This ingredient belongs to the class of Biguanides and acts via multiple mechanisms that collectively produce hypoglycemic effects. It acts on various sites as stated below:
‒ Metformin causes less production of sugar from the liver cells
‒ It increases the sensitivity of cells to insulin; this way, it removes sugar from the blood
‒ precaIt also delays intestinal sugar absorption into the bloodstream, especially after eating
This way, it controls blood sugar levels. It effectively controls the sugar level between and directly after meals.
What is Janumet?
Sitagliptin Phosphate and Metformin tablet is marketed under Janumet, among others. The working efficiency of Janumet and Istamet 50 + 500 mg tablets is the same when taken per regimen. The main point of difference between both drugs can be identified through packaging and pricing. Compare Janumet and Istamet 50 + 500 mg tablets price to save the best on your medicines.
Where can you buy Istamet 50 + 500 mg tablets online?
If you carry a valid prescription, you can order Istamet 50 + 500 mg tablet online or from a medical store at your convenience. For authentic medicine supplies and doorstep delivery, buy Istamet online from Reliablerxpharamcy at affordable prices.
How to use Sitagliptin Phosphate and Metformin tablet?
Janumet or Istamet 50 + 500 mg tablet uses - There is no fixed therapeutic regimen for treating type 2 diabetes. The dose varies according to the condition of the patient. Many factors, such as body weight, other disease conditions, and tolerance power, are assessed, and the dosage is prescribed. The usual dose starts from 50 mg Sitagliptin Phosphate/ 500 mg Metformin hydrochloride and can be increased or decreased depending upon the condition. A doctor will always recommend the best therapeutic dose to generate maximum effect with no side effects.
The combination drug should be used exactly as prescribed by your doctor. The medicine is available in the form of a tablet. Take the tablet with a full glass of water. Don't crush or chew the tablet. Regularly check your blood sugar levels. If you experience extremely low blood sugar levels, always keep a source of sugar with yourself.
How to use Sitagliptin Phosphate and Metformin tablet?
Janumet or Istamet 50 + 500 mg tablet uses - There is no fixed therapeutic regimen for treating type 2 diabetes. The dose varies according to the condition of the patient. Many factors, such as body weight, other disease conditions, and tolerance power, are assessed, and the dosage is prescribed. The usual dose starts from 50 mg Sitagliptin Phosphate/ 500 mg Metformin hydrochloride and can be increased or decreased depending upon the condition. A doctor will always recommend the best therapeutic dose to generate maximum effect with no side effects.
The combination drug should be used exactly as prescribed by your doctor. The medicine is available in the form of a tablet. Take the tablet with a full glass of water. Don't crush or chew the tablet. Regularly check your blood sugar levels. If you experience extremely low blood sugar levels, always keep a source of sugar with yourself.
Precautions with Sitagliptin Phosphate and Metformin tablet
Janumet or Istamet 50/500 mg may not be suitable if you are allergic to its active ingredient. Before taking this medicine, you should let your doctor know if you are allergic to the ingredients, have a kidney or liver disorder, have heart disease, have problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should consult their doctor before initiating treatment with this anti-diabetic drug. Some other medicines may affect the mechanism of action of this drug. Therefore, telling your doctor about all the medicines you have been using is important to ensure you get the best from your diabetes medicine. You should limit alcohol exposure as it lowers blood glucose levels. Your doctor will probably check your kidney function and blood sugar levels before and during treatment.
Side effects of Sitagliptin Phosphate and Metformin tablet
Istamet 50/500 mg is a very effective and potent anti-diabetic drug. Along with the highly therapeutic drug effect, it also exerts some side effects. It is not essential that everyone encounter side effects. If you develop any of Janumet or Istamet 50 + 500 mg tablet side effects, please talk to your doctor:
Common side effects generally happen during the initial stages of the anti-diabetic treatment include abdominal discomfort, nausea, bloating, diarrhea, nausea, flatulence, stuffy nose, joint pain, loss of appetite, throat soreness, and constipation. Some people may also experience a change in taste, like the metallic taste of the mouth. However, with the pace of time, they diminish. In case they persist or become troublesome, inform your doctor immediately.
Low blood sugar is also a possible side effect if you are taking other diabetes medicines. If you are also using other diabetes medicines, such as insulin or sulfonylureas, you should inform your doctor.
What is Istamet 50 + 500 mg used for?
Istamet 50 + 500 mg is used to treat type 2 diabetes (high blood sugar). It combines two medicines: sitagliptin, which helps your pancreas release more insulin when blood sugar is high, and metformin, which reduces the amount of sugar your liver makes and helps your body use insulin better. Your doctor prescribes it when diet and exercise alone aren't controlling your blood sugar well enough. You take it by mouth as a tablet, usually twice daily with meals.
Who is Istamet 50 + 500 mg meant for, and is it right for me?
Istamet is prescribed to adults with type 2 diabetes [a condition where your body cannot control blood sugar levels properly] when diet and exercise alone haven't worked well enough. It combines two medicines that work together to lower blood sugar. Your doctor may suggest Istamet if you're already taking metformin or sitagliptin separately, or if you need both medicines to manage your diabetes. Only your doctor can decide if Istamet is right for you, based on your blood sugar levels, kidney function, and other medicines you take. Do not start or stop any diabetes medicine without speaking to your doctor first.
How long should I keep using Istamet 50 + 500 mg?
Your doctor will determine how long you should take Istamet based on your individual needs and how well your blood sugar control improves. Type 2 diabetes is typically a long-term condition requiring ongoing treatment. Do not stop taking Istamet without discussing it with your doctor first, as suddenly stopping may cause your blood sugar levels to rise. Your doctor will review your treatment plan regularly to ensure it remains right for you and may adjust your dose or medication if needed.
Should I take Istamet 50 + 500 mg with food, and does the time of day matter?
You can take Istamet with or without food — food doesn't affect how well it works. However, taking it with a meal may help reduce stomach upset if that occurs. The time of day doesn't matter as long as you take it at the same time each day to maintain consistent medication levels. Follow your doctor's instructions about dosing schedule, as it may depend on your individual needs and how many times daily you're prescribed to take it.
What things can affect how well Istamet 50 + 500 mg works?
Several things can reduce how well Istamet works. Skipping doses or taking it irregularly weakens its effect on blood sugar control. Eating high-sugar or high-fat foods frequently can overwhelm the medicine's action. Not exercising regularly or gaining weight makes your body less responsive to the medication. Stress and poor sleep also interfere with blood sugar management. Certain other medicines, kidney problems, or liver disease can affect how your body processes Istamet. Dehydration reduces its effectiveness too. Always take your doses exactly as prescribed and discuss any lifestyle changes with your doctor to maintain the best results.
How quickly will I notice Istamet 50 + 500 mg working?
Istamet 50 + 500 mg usually takes 1–2 weeks to start lowering your blood sugar levels, though the full effect may take 2–3 months of regular use. Some people notice improvements in energy and thirst within days, while others take longer. Blood sugar control improves gradually as your body adjusts to the medicine. Your doctor will check your blood sugar levels with blood tests to confirm the medicine is working properly for you. Keep taking it as prescribed even if you don't feel an immediate difference.
Are there any serious warning signs I should watch out for with Istamet 50 + 500 mg?
Watch for these serious warning signs while taking Istamet: severe abdominal pain with vomiting, persistent unusual tiredness, difficulty breathing, or sudden swelling of face and lips. You may also experience dark urine, yellowing of eyes or skin, or muscle pain with fever. These could indicate lactic acidosis (rare buildup of acid in blood), pancreatitis (pancreas inflammation), or severe allergic reaction. Stop taking Istamet immediately and seek emergency medical help if you notice any of these signs. Contact your doctor right away—do not wait for your next appointment.
Is it safe to use Istamet 50 + 500 mg for a long period of time?
Yes, Istamet is generally safe for long-term use when taken as prescribed by your doctor. This combination medicine has been used safely in millions of patients over many years. However, your doctor will monitor you regularly with blood tests to check your kidney function and blood sugar levels, since both ingredients require periodic monitoring. Never stop taking Istamet or change your dose without speaking to your doctor first, as this could affect your blood sugar control. If you develop new symptoms or have concerns, discuss them with your healthcare provider.
Can I use Istamet 50 + 500 mg alongside my other medicines or supplements?
Istamet 50 + 500 mg can interact with certain medicines and supplements, so you need to check with your doctor or pharmacist before taking them together. Some blood pressure medicines, water pills, and certain antibiotics may affect how Istamet works or increase your risk of side effects. Always tell your healthcare provider about every medicine and supplement you're taking—including over-the-counter products and herbal remedies. They can review your full list and advise whether it's safe to combine them with Istamet.
Is it safe to drink alcohol while taking Istamet 50 + 500 mg?
Drinking alcohol while taking Istamet can increase your risk of lactic acidosis (a serious buildup of acid in your blood), especially if you drink heavily or regularly. Alcohol also lowers your blood sugar, which may cause dizziness or weakness. If you drink occasionally and in moderation, small amounts may be acceptable, but you should discuss your specific situation with your doctor first. They can advise you based on your health and how well your diabetes is controlled. Never stop taking your medicine without consulting your doctor.
Are there any groups of people who should be extra careful when using Istamet 50 + 500 mg?
You should be extra careful with Istamet if you have kidney problems, liver disease, or heart failure. Tell your doctor before starting if you're pregnant, breastfeeding, or planning pregnancy. People with a history of pancreatitis (inflammation of the pancreas) need caution. If you're over 65 or have severe infections, dehydration, or upcoming surgery, inform your doctor. Discuss all your existing medicines, as some interact with Istamet. Your doctor will check if this medicine is safe for your specific health situation.
Do I need a different dose of Istamet 50 + 500 mg if I have kidney or liver problems?
Your kidneys and liver help your body process Istamet, so their function affects your dosage. If you have kidney problems, your doctor may lower your dose or monitor you more closely, because both sitagliptin (a diabetes medicine) and metformin (another diabetes medicine) are cleared through the kidneys. Liver problems may also require dose adjustment. Never change your dose yourself—always tell your doctor about any kidney or liver issues before taking Istamet, and follow their dosing instructions exactly.
What are my options if Istamet 50 + 500 mg does not agree with me?
If Istamet 50 + 500 mg doesn't agree with you, speak to your doctor before making any changes. Your doctor may suggest taking a lower dose, switching to a different strength, or trying an alternative diabetes medicine altogether. Some people tolerate different combinations better than others. Your doctor can also check whether your symptoms are side effects or something else. Never stop taking Istamet without medical advice, as this could affect your blood sugar control. Your doctor will find the best option for your individual needs.
Which strength of Istamet 50 + 500 mg is most commonly recommended?
Istamet 50 + 500 mg is itself the most commonly recommended strength. This combines 50 mg of sitagliptin (a medicine that helps your pancreas release insulin when blood sugar rises) with 500 mg of metformin (a medicine that reduces glucose production in your liver). Your doctor may prescribe this strength as an initial dose or adjust it based on your blood sugar control and kidney function. Other strengths exist, but 50 + 500 mg is frequently used as a starting point for type 2 diabetes treatment.
How quickly can I receive Istamet 50 + 500 mg if I order from ReliableRxPharmacy?
When you order Istamet 50 + 500 mg from ReliableRxPharmacy, standard international delivery takes 20–30 business days. This timeframe applies whether you're ordering from North America or elsewhere. We source your medicine from authorised distributors of the manufacturers to ensure quality and authenticity. Delivery times may vary slightly depending on customs clearance and your location, but you can expect your order within this window.
Is it safe to buy Istamet 50 + 500 mg online, and how do I know it is genuine?
Yes, it's safe to buy Istamet 50 + 500 mg online from licensed pharmacies like ReliableRxPharmacy.com. We source all medicines, including Istamet, from authorised distributors of manufacturers, ensuring genuine products. To help ensure the medicine is authentic, purchase it only from a reputable pharmacy that complies with recognised pharmaceutical regulations and sourcing standards. Look for the one that provides contact information, a valid pharmacy registration number, and secure payment options. Ask the pharmacy for batch numbers and expiry dates. Never buy from unlicensed sellers or sites offering unusually low prices, as counterfeit medicines are a common online risk.
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