Cosart 50mg
| Pack Size | Qty | Price Per Pill or Unit | Price | Offer | ||
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| 30 Tablet/s | US$ 0.38 | US$ 11.50 |
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| 60 Tablet/s | US$ 0.31 | US$ 18.5020%US$ 23.00 |
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| 90 Tablet/s | US$ 0.31 | US$ 27.9019%US$ 34.50 |
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Description
| SKU | 631 |
|---|---|
| Generic For | Cozaar |
| Strength | 50mg |
| Manufacturer | Unichem, India |
| Active Ingredient | Losartan potassium |
Cosart 50mg for High Blood Pressure — Trusted Generic Cozaar
Cosart 50mg is a heart and blood pressure medicine containing losartan potassium, used to treat hypertension (high blood pressure) and to protect the kidneys in patients with type 2 diabetes and hypertension.
What is Cosart 50mg?
Cosart 50mg is a prescription antihypertensive tablet containing 50mg of losartan potassium. It belongs to the angiotensin II receptor blocker (ARB) class of medications and was the first ARB to receive regulatory approval. It is used to treat hypertension (high blood pressure), reduce the risk of stroke in hypertensive patients with left ventricular hypertrophy, and slow the progression of kidney disease in patients with type 2 diabetes mellitus and nephropathy. Cosart 50mg is the generic equivalent of Cozaar 50mg manufactured by Merck (MSD), with equivalent therapeutic efficacy at a significantly lower cost.
Manufacturing details: Cosart 50 mg is manufactured by Cipla Limited in WHO-GMP-certified facilities. It contains losartan potassium, produced using advanced formulation techniques and strict quality control measures to ensure safety, efficacy, batch consistency, and compliance with global pharmaceutical regulatory standards.
Losartan potassium: The active ingredient & its mode of action
Losartan potassium selectively blocks the angiotensin II type 1 (AT1) receptor. Angiotensin II is a potent vasoconstrictor produced through the renin-angiotensin-aldosterone system (RAAS). By blocking the AT1 receptor, losartan prevents angiotensin II from exerting its vasoconstrictive, aldosterone-releasing, and sodium-retaining effects, leading to vasodilation, reduced blood pressure, and reduced cardiac workload. Unlike ACE inhibitors, losartan does not inhibit bradykinin breakdown, so it does not cause the dry cough that is a common side effect of ACE inhibitors. Losartan is metabolised to an active metabolite (E-3174) that is more potent and longer-acting, providing 24-hour blood pressure control with once-daily dosing.
Clinical uses of losartan potassium
- Treat hypertension (primary high blood pressure) in adults and children aged 6 years and over.
- Reduction of risk of stroke in hypertensive patients with left ventricular hypertrophy
- Nephroprotection in patients with type 2 diabetes mellitus and hypertensive nephropathy
- Heart failure (as an alternative in patients intolerant of ACE inhibitors)
- Prevention of cardiovascular events in high-risk hypertensive patients
Brand vs generic differences
Cosart 50mg is the generic equivalent of Cozaar 50mg. Both tablets contain 50mg of losartan potassium and have been demonstrated to be bioequivalent. Generic losartan, including Cosart, is approved by major regulatory authorities worldwide and offers the same clinical outcomes as branded Cozaar at a dramatically lower price. For patients requiring lifelong antihypertensive therapy, the cost savings of switching to a high-quality generic like Cosart 50mg are substantial.
Alternative medicines & strengths of losartan potassium on ReliableRxPharmacy:
Other related medications containing losartan potassium include Cosart H 50/12.50 mg. Moreover, many other antihypertensive agents are available, such as Valzaar 40 mg and Valzaar 80mg, which should be prescribed under the supervision of a healthcare professional after analysing the patient's condition.
Key benefits of losartan potassium
- Once-daily dosing provides consistent 24-hour blood pressure control
- Well-tolerated with no cough — a significant advantage over ACE inhibitors
- Renal protective effects in diabetic nephropathy independent of blood pressure reduction
- Can be combined with diuretics, calcium channel blockers, and other antihypertensives
- Reduces left ventricular hypertrophy, decreasing long-term cardiovascular risk
- Available as a generic, making long-term hypertension management - affordable
- Extensive cardiovascular outcome data from major trials (LIFE, RENAAL, HEAAL)
Dosage regimen and administration method of losartan potassium
The usual starting dose of Cosart or Cozaar for hypertension in adults is 50mg once daily. The dose may be increased to 100 mg once daily if further blood pressure reduction is needed. In patients with intravascular volume depletion (e.g., those taking diuretics), a lower starting dose of 25mg once daily may be appropriate. For nephroprotection in type 2 diabetic patients, 50mg once daily with potential escalation to 100mg is recommended. Tablets may be taken with or without food. Moreover, it is important to follow other dietary restrictions advised by yoru healthcare specialist for tackling high blood pressure. Store at room temperature below 30°C, protected from moisture. Blood pressure should be monitored regularly throughout treatment.
Important warnings and safety guidelines associated with losartan potassium
Cosart 50mg or Cozaar is contraindicated in patients with hypersensitivity to losartan, in pregnancy (all trimesters — ARBs are teratogenic and can cause foetal harm or death), and in patients concurrently taking aliskiren (a direct renin inhibitor) in the presence of diabetes or renal impairment. Use with caution in patients with bilateral renal artery stenosis, severe hepatic impairment (dose reduction required), and hyperkalaemia. Drug interactions include potassium-sparing diuretics and potassium supplements (increased risk of hyperkalaemia), lithium (increased toxicity), and NSAIDs (reduced antihypertensive effect and increased renal risk). Monitoring of renal function, electrolytes, and blood pressure is essential during treatment.
Side effects of losartan potassium
Cosart 50mg or Cozaar is generally very well tolerated. The most common side effect is dizziness, particularly orthostatic dizziness in the early weeks of therapy. Unlike ACE inhibitors, losartan does not cause a persistent dry cough. Hyperkalaemia (elevated blood potassium) may occur, particularly in patients with renal impairment or those using potassium supplements or potassium-sparing diuretics. Fatigue, headache, and back pain are occasionally reported. Rare but serious adverse effects include angioedema (rare, but cross-reactivity may occur in patients with ACE inhibitor-induced angioedema), significant hypotension in volume-depleted patients, and renal dysfunction. Foetal and neonatal toxicity is severe if used in pregnancy.
Benefits of buying losartan potassium medicine online from ReliableRx
Hypertension requires lifelong management, making medication cost a significant concern for patients. ReliableRxPharmacy offers Cosart 50mg (losartan generic) at prices far below those of branded Cozaar, enabling patients to manage their blood pressure without financial hardship. The convenience of online ordering, combined with discreet packaging and reliable worldwide shipping, makes ReliableRxPharmacy a trusted platform for managing chronic conditions. Products are sourced from Cipla, a globally certified manufacturer, with full product transparency available on the website.
What is Cosart 50mg used for?
Cosart 50mg is used to treat high blood pressure (hypertension), reduce stroke risk in at-risk hypertensive patients, and protect the kidneys in patients with diabetic nephropathy.
Does Cosart 50mg cause a cough?
No. Unlike ACE inhibitors (e.g., Ramipril, Lisinopril), losartan does not inhibit bradykinin breakdown and therefore does not cause the dry cough associated with ACE inhibitors.
When is the best time to take Cosart 50mg?
Cosart 50mg can be taken at any time of day, with or without food. Consistency is key — take it at the same time each day to maintain stable blood pressure control.
Can I take Cosart 50mg during pregnancy?
No. ARBs, including Losartan, are contraindicated during pregnancy. They can cause serious foetal harm or death. Effective contraception is essential for women of childbearing age on losartan.
Can I stop Cosart 50mg when my blood pressure is normal?
No. Normalised blood pressure indicates the medication is working. Stopping without medical advice risks rebound hypertension. Always consult your doctor before changing or stopping therapy.
Is Cosart 50mg safe for patients with kidney disease?
Losartan has specific renal protective benefits in diabetic nephropathy. However, in patients with severe renal impairment or bilateral renal artery stenosis, it requires careful monitoring and dose adjustment.
How long does it take for Cosart 50mg to lower blood pressure?
Blood pressure reduction begins within hours of the first dose, but the maximum antihypertensive effect is typically reached after 3–6 weeks of treatment.
Can I take Cosart 50mg with other blood pressure medications?
Yes, losartan is frequently combined with diuretics or calcium channel blockers for better blood pressure control. However, combining with another RAAS blocker is generally avoided.
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