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Irovel H 150/12.50 mg

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SKU 546
US Brand Name Avalide
Strength 150/12.50mg
Generic Name Irbesartan HCTZ


Description of the drug

Irbesartan Hydrochlorothiazideis the main active pharmaceutical ingredient present in Irovel H 50/12.5 mg tablets. This drug is used to treat hypertension as well as swelling due to fluid accumulation. Irbesartan is an angiotensin II receptor antagonist (type AT1) that helps in relaxing the blood vessel and widen up by blocking the substances that cause a blood vessel to tighten and lowers the blood pressure. Hydrochlorothiazide is a water pill, a diuretic that helps in urination.

Indications and Usage

Irovel Hydrochlorothiazide is a combination drug, which is indicated for the treatment of lowering blood pressure as well as a diuretic, it lowers the blood pressure reduces the risk of heart attack in patients having hypertension and an enlarged heart, it also protects the kidney from damage due to diabetes and helps to remove extra salt and water. Irbesartan helps in lowering blood pressure and Hydrochlorothiazide helps in urination.

Dosage and Administration

- Recommended dose:

Always take this medication exactly as your doctor prescribed.

- Method of Administration:

Irovel-H is available is the form of a tablet to be taken orally by mouth once a day before or after having a meal as prescribed by the doctor. Drinking extra amount of water will be helpful and usually recommended by the doctor. Before buying Irovel H online, it is necessary to do a thorough research on its ingredients.

- Missed dose

If you miss one or more doses; take the next dose on time.Do not take more than your doctor is prescribed.

- Overdose

The overdose of any drug can cause severe effects. The overdose may cause fast or slow heartbeat, dizziness, lightheadedness, blood electrolyte problems, muscle pain, weakness and many other allergic symptoms. In any case, of overdose, you should immediately contact your doctor.

Forms and Strengths

The drug IrbesartanHydrochlorothiazide is available in the following strength under the brand name of:

  1. Irovel H 150/12.50 mg
  2. CoAprovel
  3. Irovel 150 mg
  4. Irovel 300 mg


  • Do not take this drug with Aliskiren in pateints those who are having diabetes
  • Do not take this medicine if patient is suffering from Anuria, a condition when the kidney fails to produce urine
  • This drug is not suitable for those patients having a high level of potassium in his/her blood

Warnings and precautions

  • Remember that Irbesartan and Hydrochlorothiazide cannot be consumed by patients who are allergic to the medicine and its ingredients. Before buying Irovel H 50/12.50 mg tablets online, it is necessary to do a thorough research on its ingredients.
  • If a patient is suffering from any kind of liver and kidney problem, this drug is harmful to this condition, so avoid taking it this drug
  • If a patient has suffered recently with excessive vomiting and/or diarrhea, this drug may worsen the condition therefore, consult your doctor before taking this medicine
  • This drug is not suitable for those patients having a high level of potassium in his/her blood 
  • This drug is not suitable for pregnant and breastfeeding woman, it may cause fatal effects to infant.
  • Do not take this drug if the patient is having or had the problem of swelling of the face, lips, throat and tongue
  • Do not take any prescribed or non-prescribed drug with this medicine, consult your doctor first about your medical history before starting up this medication.
  • Do not drive or use any machinery because using these tablets may have a minor or moderate effect on your ability to drive and using of machines. They may cause dizziness, so avoid driving and use of machines, while taking this drug
  • If you have a history of stroke or a recent heart attack than consult your doctor before taking this medicine
  • This drug may take 2 to 4 weeks to show its effect, so do not stop this medication or change your dose without consulting your doctor.

Side effects

  • Tell your doctor if you have any side effects that bothers you or does not go away.
  • Low blood pressure
  • Fatigue
  • Stomach pain
  • Diarrhea
  • Nausea
  • Vomiting
  • Hives 
  • Itching 
  • Rash
  • Runny or stuffy nose
  • Some uncommonu side effect can occur:
  • Eye pain, vision problem
  • Very rapid and irregular heartbeat, brain attack (stroke)
  • Inflammation of the liver
  • Anaemia low number of red blood cells
  • Reduced number of platelets which may lead to easy bruising
  • Ringing in the ears
  • Migraine
  • Changes in kidney function
  • Flu-like symptoms
  • Back pain and urinary tract infection
  • Sensitivity to light
  • Depression 
  • Low sodium levels in the blood
  • Jaundice

Drug Interactions

  • These are the drugs that can alter the pharmacological effect of Irbesartan and Hydrochlorothiazide:
  • Diuretics eg. furosemide
  • Potassium-sparing diuretics like amiloride, spironolactone or potassium supplements because of the risk of high blood potassium level
  • Lithium, a drug used to treat certain mental disorders
  • Non-steroidal and anti-inflammatory painkillers (such as ibuprofen, or diclofenac)
  • COX-2 inhibitors like celecoxib, etoricoxib
  • Other blood pressure lowering medicines it may cause additional reduction in the blood pressure
  • ACE inhibitors such as captopril and lisinopril
  • Dofetilide or Ketanserin using this drug with these may cause irregular or increased heartbeat 
  • Ask your doctor and get the full list of drugs that may increase the possibility of drug interactions or interfere with the effectiveness of Irovel H.


Irovel H150/12.50 mg tablet comprises of two active pharmaceutical ingredients called Irbesartanand and Hydrochlorothiazide. Irbesartan is an angiotensin II receptor blocker (type AT1) helps in lowering blood pressure. It dilates and relax the blood vessel to increase the blood flow to the heart. Hydrochlorothiazide is a thiazide diuretic, helps kidney to remove fluid from the body, which lowers the blood pressure and helps the heart to pump the heart more effectively.

Storage information

Irbesartan Hydrochlorothiazide tablets should be stored in a safe place that is away from heat and moisture. Do not refrigerate. Keep it out of the reach of children and pets. Do not keep the tablets out in open.


IrovelH tablets are manufactured by Sun Pharmaceuticals Private Limited, an Indian multinational pharmaceutical company, located in Mumbai, India.s

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