Aprezo 30mg

Apremilast

Aprezo 30mg

$0.56 - $0.67

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30 Tablet/s US$ 0.67 US$ 20.00
60 Tablet/s US$ 0.58 US$ 35.0012%US$ 40.00
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90 Tablet/s US$ 0.56 US$ 50.0017%US$ 60.00
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Description

SKU 2134
Generic For Otezla
Strength 30mg
Manufacturer Glenmark, INDIA
Active Ingredient Apremilast

Aprezo 30mg (Apremilast) — Trusted Generic Otezla

Aprezo 30 mg is a prescription medicine for adults with the following conditions:

     –     Active psoriatic arthritis: If you can’t use another type of medication called disease-modifying antirheumatic drugs (DMARDs) or when you have tried one of these drugs and it is not effective.

     –     Moderate to severe chronic plaque psoriasis: If you can’t use one of the following therapies or when you have tried one of these treatment options, and it is not effective enough:

                     – Phototherapy: a treatment where certain skin areas are exposed to ultraviolet light.

                    – Systemic therapy: This treatment affects the entire body rather than just one area. It includes ciclosporin, methotrexate, or psoralen.                  

     –     Behcet’s disease: For treating mouth ulcers, a common problem for people with this illness.

Psoriatic arthritis, psoriasis, and Behcet’s disease are usually lifelong conditions, and there is currently no cure for these conditions. Aprezo contains the active ingredient Apremilast, which reduces the action of certain enzymes in the body involved in the inflammation process. By interfering with the activity of the enzyme called phosphodiesterase 4, Aprelimast can help to control the inflammation related to psoriatic arthritis, psoriasis, and Behcet’s disease, thereby reducing the signs of these conditions.  

In the case of psoriatic arthritis, Aprezo results in an improvement in swollen and painful joints and can improve physical function. It is extremely beneficial for patients with an early stage of the disease progression in the case of rheumatoid arthritis.

In patients with psoriasis, this treatment causes a significant reduction in psoriatic skin plaques as well as other signs of the disease. The oral treatment is convenient and will help transform the psoriasis treatment regime.

In the case of Behcet’s disease, this medicine minimizes the number of mouth ulcers and can stop the occurrence completely. It can also reduce the associated pain.

Apremilast has been shown to improve the quality of life in such patients. This means that the impact of these conditions on daily activities, relationships, and other factors should be less than before.   

Aprezo is for oral use. Swallow the tablet, preferably with a glass of water. You can take these pills either before or after consuming food. Take one tablet in the morning and one in the evening. You should continue taking the medicine until your health professional advises you. 

Do not take Aprezo if allergic to Apremilast or other medicine ingredients. The use of this medication is contraindicated in patients in case of pregnancy. Apremilast has not been studied in children and adolescents; therefore, it is unsuitable for children and adolescents aged 17.  

Let your healthcare provider know if you are taking antibiotics for tuberculosis, medications used for the treatment of seizures or epilepsy, and St.John’s wort, a herbal medication for mild anxiety and depression.   

 

Very common side effects of the medicines include nausea, headache, diarrhea, and upper respiratory tract infections, including cold, runny nose, and sinus infections.

Common side effects of the medicine include back pain, cough, trouble sleeping, loss of appetite, migraine, tension headache, stomach pain, depression, migraine, frequent bowel movements,   vomiting, back pain, inflammation, and swelling of the tubes in your lungs, indigestion or heartburn.

Seek immediate medical help if any of these side effects become troublesome or persist for longer. However, people receiving Aprezo 30 mg may rarely experience changes in behavior or mood, suicidal behavior, and feelings of depression. 

What is Aprezo 30mg used for?

Aprezo 30mg contains apremilast, a medicine that reduces inflammation [swelling and irritation] in your body. You take it to treat psoriasis (a skin condition causing red, scaly patches), psoriatic arthritis (joint pain and swelling linked to psoriasis), and behçet's disease (a condition causing mouth ulcers and skin sores). Apremilast works by calming your immune system's inflammatory response. Your doctor will prescribe Aprezo 30mg as part of your personalized treatment plan based on your specific condition and health needs.

How does Aprezo 30mg work in the body?

Aprezo 30mg contains apremilast, which works by blocking enzymes called phosphodiesterase-4 inhibitors (proteins that control inflammation signals in your body). By slowing these enzymes, apremilast reduces the production of inflammatory chemicals [substances that cause swelling and irritation] that trigger skin and joint problems. This helps decrease inflammation and symptoms associated with conditions like psoriasis and psoriatic arthritis [joint pain linked to psoriasis].

How long should I keep using Aprezo 30mg?

Your doctor will decide how long you should take Aprezo 30mg based on your condition and how well it works for you. Some people take it long-term to manage their symptoms, while others may take it for a shorter period. Do not stop taking Aprezo without talking to your doctor first, even if you feel better, as stopping suddenly could affect your treatment. Your doctor may adjust your dose or duration depending on how you respond to the medicine.

What should I do if I forget to take a dose of Aprezo 30mg?

If you forget to take a dose of Aprezo 30mg, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and take your next dose at the usual time. Never double up on doses to make up for a missed one. If you're unsure about what to do, contact your doctor or pharmacist for guidance. Setting a daily alarm can help you remember to take your tablet at the same time each day.

What things can affect how well Aprezo 30mg works?

Several things can affect how well Aprezo 30mg works for you. Taking it with food may improve how your body absorbs it, so try to take it consistently with meals. Other medicines, especially those that affect liver function (cytochrome P450 inducers), can reduce Aprezo's effectiveness—always tell your doctor about all medicines you take. Your liver and kidney function matter too; if these organs don't work normally, the medicine may not work as well. Smoking and heavy alcohol use may also reduce its effectiveness. Consistently taking your doses as prescribed is essential for best results.

How will I know if Aprezo 30mg is working for me?

You'll know Aprezo 30mg is working when you notice improvements in your psoriasis or psoriatic arthritis symptoms. Look for reduced skin redness, scaling, and plaques [thick patches], or decreased joint pain and swelling. Some people see changes within weeks, while others take several months. Keep track of how your skin feels, how easily you move, and any reduction in itching. Your doctor can also monitor your progress during check-ups. If you're not seeing improvement after three months, discuss this with your doctor—they may adjust your dose or try a different approach.

What are the common side effects of Aprezo 30mg, and should I be worried?

Most people taking Aprezo 30mg experience mild side effects that often improve as your body adjusts. The most common are diarrhoea, nausea, and headache. You may also notice weight loss, vomiting, or upper respiratory infections. These effects are usually temporary and manageable. However, if side effects persist, worsen, or significantly affect your daily life, contact your doctor immediately. Never stop taking Aprezo without medical advice, as this could affect your treatment. Report any severe or unusual symptoms to your healthcare provider right away.

Is it safe to use Aprezo 30mg for a long period of time?

Long-term use of Aprezo (apremilast) is generally considered safe when taken as prescribed by your doctor. This medicine has been studied in clinical trials lasting months to years, and it's commonly used for extended periods to manage conditions like psoriasis and psoriatic arthritis [inflammation of joints and skin]. Your doctor will monitor you regularly during long-term treatment to check for any side effects and ensure the medicine continues working well for you. Always take it exactly as directed and attend scheduled check-ups so your doctor can assess your ongoing safety and response to treatment.

Which medicines should I avoid while using Aprezo 30mg?

Aprezo can interact with certain medicines, so tell your doctor about all medications you're taking. Key medicines to avoid or use with caution include strong CYP3A4 inducers (medicines that speed up how your body processes Aprezo, making it less effective), such as rifampicin and St. John's Wort. Also inform your doctor if you take medicines for depression, heart conditions, or immune system disorders. Never stop or change any medicine without consulting your doctor first, as they need to assess whether combinations are safe for you and adjust doses if needed.

Can vitamins or herbal remedies interfere with Aprezo 30mg?

Some herbal remedies may interfere with how Aprezo (apremilast) works in your body. St. John's Wort, commonly used for mood support, can reduce Aprezo's effectiveness. Other supplements might affect your liver's ability to process this medicine. Before taking any vitamins, herbal remedies, or dietary supplements alongside Aprezo, discuss them with your doctor or pharmacist. They can check whether specific products are safe to combine with your treatment and adjust your care if needed. Do not start or stop any supplements without medical guidance.

Can older adults or children use Aprezo 30mg safely?

Aprezo 30mg is not recommended for children because safety and effectiveness haven't been established in this age group. Older adults can use Aprezo safely, but your doctor may adjust your dose based on kidney function, which naturally changes with age. Older adults may also be taking other medicines, so your doctor will check for possible interactions. Always tell your doctor your age and any other health conditions or medicines before starting Aprezo to ensure it's safe for you.

Do I need a different dose of Aprezo 30mg if I have kidney or liver problems?

Kidney or liver problems may affect how your body processes Aprezo 30mg. Your doctor needs to know about any kidney or liver issues before you start taking this medicine, as dose adjustments may be necessary. Do not change your dose yourself—your doctor will decide the right dose for you based on how well your kidneys and liver work. Always tell your doctor about any existing liver or kidney conditions, and inform them of any new problems that develop while taking Aprezo. Regular monitoring may be needed.

What are my options if Aprezo 30mg does not agree with me?

If Aprezo 30mg doesn't agree with you, talk to your doctor straight away. They may lower your dose, suggest taking it with food, or adjust when you take it. Your doctor might also prescribe a different medicine altogether if Aprezo isn't right for you. Never stop taking Aprezo without speaking to your doctor first, as this could affect your treatment. Keep notes of what's bothering you so you can explain clearly to your doctor.

How does Aprezo 30mg compare to other treatments used for the same condition?

Aprezo (apremilast) works differently from other treatments for psoriasis and psoriatic arthritis. Unlike biologics that target specific immune proteins, apremilast works inside cells to reduce inflammation-causing substances. Some patients prefer it because it's taken by mouth rather than injected. However, it may work more slowly than biologics for severe cases. Your doctor will choose based on your condition's severity, other health issues, and how your body responds. Only your doctor can advise which treatment suits you best.

How do I safely dispose of leftover or out-of-date Aprezo 30mg?

Do not throw Aprezo 30mg tablets in the bin or flush them down the toilet. Take unused or out-of-date tablets to your local pharmacy — they have safe disposal systems for medicines. Your pharmacist will dispose of them properly without harming the environment. If your pharmacy doesn't offer this service, contact your local waste management authority for guidance on medicine disposal in your area.

How should I store Aprezo 30mg at home, and what happens if it expires?

Keep your Aprezo 30mg tablets in a cool, dry place away from direct sunlight and heat. Store them at room temperature in their original container with the lid tightly closed. Keep the tablets away from moisture, such as bathrooms. If your Aprezo expires, do not use it. Expired medicine may not work effectively or could be unsafe. Dispose of expired tablets at a pharmacy or following your local medicine disposal guidelines. Always check the expiry date before taking a dose.

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