Perinorm 10 mg is indicated for the treatment of adults for 2 to 12 weeks to relieve heartburn symptoms with gastrointestinal reflux disease (GERD) when certain other medications do not work. GERD occurs when the stomach in acid flows up, causing heartburn. It may harm your oesophagus (the tube that joins your mouth and stomach). It is also effective at relieving the symptoms of slow stomach emptying in people suffering from diabetes mellitus. The medicine contains the active ingredient Metoclopramide which increases the movement of the contraction of the stomach and intestine. It helps you eliminate symptoms such as nausea, vomiting, a feeling of fullness after meals, heartburn, and loss of appetite.

Take Perinorm exactly as your doctor tells you. Avoid making changes to your dosing regimen unless instructed. The medicines come in tablet form that you take orally with a glass of water. You should not take medicine for more than twelve weeks. Take the tablet at least thirty minutes before each meal at bedtime. Do not consume alcohol while taking the medication. Alcohol may worsen some side effects of the medicine, such as feeling sleepy. Avoid driving, operating machinery, or other dangerous activities until you know how Metochlopramide affects you. This medicine can cause sleepiness or dizziness.        

Treatment can cause tardive dyskinesia, a serious movement disease that is often irreversible. The risk of developing the condition increases with the duration of treatment. The treatment should be discontinued in patients who develop signs and symptoms of tardive dyskinesia. Do not take Perinorm if you have stomach problems that could worsen with this medicine, such as blockage, bleeding or a tear in the gut or bowel wall. Avoid taking medicine if you have pheochromocytoma, a tumour that can contribute to high blood pressure. You should not take Metoclopramide if you have epilepsy. The medicine can increase your chance of seizures and make them worse.

Before taking Perinorm, let your doctor know if it can cause serious allergic reactions. Discontinue treatment immediately and get immediate medical help if you develop symptoms such as tongue/lips/tongue swelling, ultimately leading to swallowing and breathing. Before taking this medication, let your doctor know about all medical conditions, including if you have diabetes, Parkinson’s disease, kidney problems, liver problems, high blood pressure, heart rhythm problems/heart problems, seizures, breast cancer, drinking alcohol, or are pregnant or breastfeeding. Inform your doctor about all the medicines you take, including prescription, and non-prescription medicines, vitamins and herbal solutions. Especially inform your doctor if you take another medicine containing Metochlropramide, Parkinson’s, blood pressure, antidepressants, antipsychotic drugs, insulin, anti-anxiety medicines, sleep medications and narcotics. It is not recommended for use in children.       

The most common side effects of Perinorm include drowsiness, restlessness, tiredness, and lack of energy. You may have more side effects the longer you take Perinorm and the more of this medication you take. Call your doctor and get immediate medical help if you:

    — Have muscle movements that you can’t stop or control

    — Have a high fever, thinking problems, stiff muscles, fast/irregular heartbeat, and increased sweating

    — Have new or unusual muscle movements

    — Feel depressed or have suicidal thoughts 

Tell your doctor about any side effects that become bothersome or do not go away. These are not all the possible adverse effects of this medicine.