Misoprost 200 mcg prevents bleeding immediately after childbirth (postpartum haemorrhage) in women when oxytocin (a commonly prescribed injectable treatment) is unavailable. It contains the active ingredient Misoprostol, which is also given for induction of labour and treatment of incomplete abortion. The medicine may also be used with another agent called mifepristone for abortion.  

The recommended dose is one of 3 tablets of oral Misoprostol 200 mcg. To ensure full dose administration, swallow the tablet and do not crush or break it.

For labour induction, dissolve one Misoprost 200 mcg tablet in 200 ml of water and take 25 ml of that solution, equivalent to 25 mcg misoprostol, as a single dose. Take each dose after two hours until labour starts.  

For treatment of missed abortion, the recommended dose is three tablets of Misoprostol 200 mcg tablet.  

For treatment for medical abortion less than seven weeks (49 days) of pregnancy  

Take the medicine under a doctor’s supervision experienced in treating pregnant women and medical abortion.  

First, you may be advised to take another medicine, Mifepristone 200 mcg orally. Then, 24 to 48 hours later, take two tablets of Misoprostol 200 mcg as a single dose.

Concomitant intake of food may reduce blood levels of this medicine. Therefore, Misoprost should preferably be taken on an empty stomach. However, it can be taken without consideration of food intake if required in life-threatening situations. The medicine should not be adjusted if your kidney or liver function is impaired.

Do not take Misoprost 200 mcg tablets if allergic to Misoprostol or other medicine ingredients. Also, avoid taking the medicine if you:

    –   Have had previous allergic reactions to prostaglandins.

    –   Hypersensitivity to any ingredient of the combination treatment

    –   With severe liver diseases

    –   With inherited porphyria (a rare metabolic disorder)

    –   With acute failure of the adrenal gland

    –   In whom the embryo is known or suspected to grow outside the uterus

    –   These tablets must not be used for abortion in women.

Speak to your doctor before taking Misoprostol tablets if you have heart disease, have bleeding disorders, or have been using corticosteroids (to reduce inflammation).  

Misoprostol tablets should not be given to children below pubertal age.   

Headache, tiredness, and dizziness have been reported while receiving Misoprostol tablets. If you develop these symptoms, you should avoid potentially hazardous tasks such as driving or operating machinery.   

Like all medicines, Misoprost 200 mcg can give rise to side effects, although not everybody gets them. The side effects observed after Misoprost intake include:

Common side effects are nausea (feeling sick), headache, dizziness, vomiting, diarrhoea, chills, shivering, and fever.

When used for induction of labour, uterine cramping and rupture, as well as distress to the unborn, may occur. When used for abortion, prolonged menstrual-like bleeding and incomplete embryo expulsion have been reported.