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| 8 Tablet/s | US$ 3.75 | US$ 30.00 |
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| 24 Tablet/s | US$ 2.50 | US$ 60.0033%US$ 90.00 |
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| 32 Tablet/s | US$ 2.50 | US$ 80.0033%US$ 120.00 |
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| 48 Tablet/s | US$ 2.50 | US$ 120.0033%US$ 180.00 |
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Description
| SKU | 165 |
|---|---|
| Generic For | Dostinex |
| Strength | 0.5 mg |
| Active Ingredient | Cabergoline |
Cabgolin 0.5 mg for Women'S Health — Trusted Generic Dostinex
Cabgolin 0.5mg is a dopamine agonist containing cabergoline as its active ingredient. It is widely used to treat hyperprolactinaemia and related disorders. Cabgolin 0.5mg is a cost-effective generic alternative to Dostinex (Pfizer) and is available with discreet worldwide shipping.
What is Cabgolin 0.5mg?
Cabgolin 0.5mg is a prescription medication containing cabergoline, a potent long-acting dopamine D2 receptor agonist. Cabgolin 0.5mg is indicated primarily for the treatment of hyperprolactinaemia, a condition characterised by abnormally elevated blood prolactin levels. It is also used to treat prolactin-secreting pituitary tumours (prolactinomas) and associated conditions such as amenorrhoea, galactorrhoea, and infertility in women, and hypogonadism in men.
Manufacturer: Sun Pharmaceutical Industries, one of India's most respected pharmaceutical companies.
The mechanism of action of cabergoline(active ingredient)
Cabergolin acts as a selective dopamine D2 receptor agonist in the pituitary gland. Dopamine naturally inhibits prolactin secretion from the lactotroph cells of the anterior pituitary. By mimicking dopamine's action, cabergoline strongly suppresses prolactin synthesis and release. Its high selectivity for D2 receptors and its extremely long half-life of 63–69 hours allow for effective prolactin suppression with just twice-weekly dosing. This long duration of action distinguishes cabergoline from older dopamine agonists such as Bromocriptine, which requires more frequent dosing and has a higher side effect burden. Normalisation of prolactin levels restores ovarian/testicular function and resolves associated symptoms.
Clinical uses of cabergoline Cabgolin
- Idiopathic hyperprolactinaemia
- Prolactin-secreting pituitary microadenomas and macroadenomas - (prolactinomas)
- Amenorrhoea (absent menstrual periods) caused by high prolactin levels
- Galactorrhoea (inappropriate milk secretion) in non-breastfeeding individuals
- Female infertility due to hyperprolactinaemia
- Hypogonadism in men is associated with elevated prolactin
- Inhibition of physiological lactation (suppression of breastfeeding)
- Off-label: Parkinson's disease (as adjunctive dopaminergic therapy)
Brand vs generic differences
Cabgolin 0.5mg is a generic equivalent of Dostinex 0.5mg manufactured by Pfizer. Both contain the same active ingredient, cabergoline, at the same dose, and must meet stringent bioequivalence standards set by regulatory authorities. Sun Pharmaceutical Industries is a globally recognised, WHO-GMP-certified manufacturer, ensuring that Cabgolin meets quality standards comparable to those of the innovator product. The key difference is cost: Cabgolin 0.5mg is substantially more affordable than Dostinex, making ongoing treatment financially sustainable for patients who require long-term therapy.
Alternative medicines & strengths on ReliableRxPharmacy
ReliableRxPharmacy also stocks Cabgolin 0.25mg for patients requiring a lower starting dose or those undergoing dose titration.
Key benefits
- Highly effective at reducing elevated prolactin levels to within the normal range
- Twice-weekly dosing schedule greatly improves patient compliance
- Significantly better tolerated than older alternatives such as Bromocriptine
- Shrinks prolactin-secreting pituitary tumours in the majority of patients
- Restores menstrual cyclicity and ovulation in women with hyperprolactinaemia
- Improves libido and sexual function in men with elevated prolactin
- Long-established safety record with extensive clinical data spanning over 30 years
Dosage advice for using cabergoline
The initial recommended dose of Cabgolin or Dostinex for hyperprolactinaemia is 0.5mg per week, given as a single dose or split into two 0.25mg doses (half a tablet) twice weekly. The dose may be increased gradually at monthly intervals by 0.5mg per week, up to a maximum of 3mg per week, depending on prolactin response. Tablets should be taken with food to reduce nausea. Store at room temperature below 25°C, away from light and moisture. Regular monitoring of serum prolactin levels and cardiac evaluations (echocardiography) is recommended during long-term therapy. Do not discontinue without consulting your endocrinologist.
Precautions and safety advice for using cabergoline
Cabgolin 0.5mg or Dostinex is contraindicated in patients with hypersensitivity to cabergoline or other ergot derivatives. It should not be used in patients with uncontrolled hypertension or puerperal hypertension. Cardiac valvulopathy (heart valve problems) has been associated with long-term, high-dose cabergoline use; echocardiographic monitoring is recommended for patients receiving prolonged therapy. Cabergoline interacts with antipsychotic medications (dopamine antagonists) that reduce its efficacy, and with antihypertensives that may cause excessive blood pressure reduction. Patients with hepatic impairment require dose adjustments. Cabergoline should not be used in women with postpartum psychosis and should be used with caution during pregnancy — consult a specialist before use.
Side effects related to cabergoline
Cabgolin 0.5mg or Dostinex is generally well tolerated. The most common side effects are nausea, headache, and dizziness, particularly at the initiation of therapy. Gastrointestinal symptoms, including vomiting, constipation, and abdominal discomfort, may occur but typically resolve with continued use or dose reduction. Orthostatic hypotension (a drop in blood pressure upon standing) can occur, especially with first doses. Less common effects include fatigue, nasal congestion, and transient elevations of liver enzymes. With prolonged high-dose use, serious but rare side effects include cardiac valvulopathy, impulse control disorders (compulsive behaviours such as gambling), and pleuropulmonary fibrosis. Patients should report any new compulsive behaviours or breathlessness to their doctor promptly.
Benefits of buying this medicine from ReliableRxPharmacy
Purchasing Cabergoline pills online enables patients to access affordable, high-quality treatment. Cabergoline is a speciality medication that can be expensive in branded form; the generic Cabgolin offers the same clinical benefit at a fraction of the cost. Leading online pharmacies like ReliableRxPharmacy ship discreetly and securely to destinations worldwide, including the UK, USA, Australia, and Canada. The platform provides detailed product information and responsive customer support, making it a reliable choice for patients managing long-term hormonal conditions. All medications are sourced from WHO-GMP certified manufacturers.
What condition does Cabgolin 0.5mg treat?
Cabgolin 0.5mg treats hyperprolactinaemia — abnormally high prolactin levels — and related conditions, including amenorrhoea, galactorrhoea, infertility, and prolactinomas.
How often do I take Cabgolin 0.5mg?
Typically twice weekly. Your endocrinologist may adjust the dose based on your serum prolactin levels and clinical response over monthly assessments.
How long does it take for Cabgolin to lower prolactin levels?
Prolactin levels typically begin to fall within the first week of treatment, with significant normalisation often achieved within 4–8 weeks of therapy.
Can Cabgolin 0.5mg help restore my menstrual cycle?
Yes, normalising prolactin levels with Cabergolineoften restores regular menstrual cycles and ovulation in women with hyperprolactinaemia-induced amenorrhoea.
Is it safe to use Cabgolin 0.5mg long-term?
Long-term use requires cardiac monitoring by echocardiography to check for valve changes. Your specialist will determine whether continued therapy is appropriate and safe.
Can Cabgolin 0.5mg be used during pregnancy?
Cabergoline should generally be discontinued once pregnancy is confirmed. Consult your endocrinologist, as some women with macroadenomas may require continued treatment under specialist supervision.
What is the difference between Cabgolin 0.25mg and 0.5mg?
Cabgolin 0.25mg is used for initial low-dose therapy or fine dose titration, while 0.5mg is the standard maintenance dose for most patients with hyperprolactinaemia.
Does Cabgolin 0.5mg cause weight gain?
Weight changes are not a commonly reported side effect of cabergoline. However, underlying hormonal changes related to hyperprolactinaemia may affect weight independently of the medication.
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