Pyzina 750 mg


US$ 0.50

In stock
Pack Size Qty Price Per Pill or Unit Price Offer
30 Tablet/s US$ 0.50 US$ 15.14
60 Tablet/s US$ 0.50 US$ 30.27
90 Tablet/s US$ 0.50 US$ 45.41



SKU 843
US Brand Name Pyzina
Strength 750mg
Generic Name Pyrazinamide
Manufacturer Lupin


Pyrazinamide is a synthetic and potent drug used in the treatment of tuberculosis (TB). It stops the bacterial growth and cures the infection. It belongs to the pyrazine analogue of nicotinamide. It is well absorbed from the gastrointestinal tract and 70% of the drug is excreted through urine. It gets converted into its active form pyrazinoic acid in body and produces the therapeutic effect. It is a first line anti TB drug and is a vital component of DOTS (Directly observed treatment short course) used for the management and treatment of Tuberculosis.

The ailments it is used for:

Pyrazinamide is an antibiotic given in the treatment of tuberculosis. Pyrazinamide is given in the first two months of treatment as it decreases the duration and is also given in the latent tuberculosis. Off label use of the drug is in the diagnosis of indications like hyperurecimia and hyperuricosuria.

Understanding the drug Pyrazinamide:

Pyrazinamide is a potent antibiotic that fights bacterial infection.

How it works?

Pyrazinamide is a prodrug that gets converted into its active form by the action of enzyme pyrazinamidase. Pyrazinoic acid gets accumulated inside the mycobacterium cell wall at acidic pH than at neutral pH. The accumulation of pyrazinoic acid disrupts membrane potential and interferes with the energy production. It shortens the treatment duration of Tuberculosis.

When should you avoid it?

You should not take Pyrazinamide if you:

  • Are allergic to Pyrazinamide
  • Have jaundice or other liver disease
  • Have kidney problems
  • Are suffering from diabetes
  • Have gout
  • Have high uric acid concentration in blood
  • Are pregnant or planning to conceive
  • Are breastfeeding

How much to take?

The dosage is solely decided by the Doctor after assessing your condition and various factors such as disease condition, age, body weight and gender. One can’t fix the dose as it varies from patient to patient. Always take the dose as prescribed by the Doctor.

What are the strengths available?

Pyrazinamide is available in following strength preparation on our website:

  • Pyzina 500 mg
  • Pyzina 750 mg

Who is the manufacturer?

Pyzina is manufactured by Lupin Pharmaceuticals Inc, a reputed pharmaceutical giant and is available on our website in the pack of 30, 60 and 90 tablets.

How to take?

Pyrazinamide is taken exactly as prescribed by your doctor.  Swallow the tablet with full glass of water. Don’t crush or chew the tablet. Take the medicine timely and complete full course of the treatment.

When to take?

Always take the medicine as instructed by the Doctor or Pharmacist. Don’t consume the medicine in a greater amount. The dose intake varies from patient to patient. So, doctor will recommend the best therapeutic dose for you. Consult your doctor before taking the drug.

For how long should it be taken?

Take the medicine as long as recommended by the Doctor. Always ask the doctor before stopping the intake of the drug.

What if you take too much (overdose)?

If overdose, immediately consult with your concerned doctor. Take medical help as soon as possible if you encounter any unusual reaction.

What if you miss the dose?

Try to take the medicine at the same time each day. This reduces the chances of missing dose. Talk to your Doctor if you miss the dose. Don’t double up the dose in order to catch up with the previous one.

What are the side effects?

Every medicine shows some side effects, same way this drug also have some undesired effects with it. Pyrazinamide shows common side effects such as:

  • Mild diarrhea
  • Stomach upset
  • Fatigue

Some serious and rare side effects that need serious consideration are stated below:

  • Skin rashes
  • Fever
  • Difficulty in urine
  • Pain and swelling in the joints
  • Yellowing of skin and eyes
  • Unusual bleeding and bruising

Are there any possible drug interactions?

Always inform your doctor about the drugs you are taking till date. Give a complete list of prescription or non prescription drugs and any other disease conditions. This way, doctor is able to decide and give you the list of drugs and other things that may interact with Pyrazinamide.

What are the things to be taken care of?

  • Always take the medicine as per prescription
  • Don’t use the expired drug
  • Pyrazinamide  can cause diarrhea, stop taking the medicine and consult your doctor if you experience watery and bloody diarrhea
  • Avoid alcohol beverages while using this medicine
  • Don’t share your medicine with anybody, even if they have the same symptoms
  • Always store the medicine at the room temperature and away from moisture, heat and light
  • Consult with your pharmacist about the proper disposal of the drug
  • Keep a complete record of all the medicines you are taking along with this medicine
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