Pangraf 1 mg is a prescription medicine to avoid the rejection of transplanted organs. Organ transplantation is the only treatment opted for end-stage organ failures such as liver and heart failure. Doctors remove the organ either from a living donor or donor who has died. It is one of the most trusted medicines recommended in organ transplantation. It can be taken alone or along with the other medicines to avoid rejection of any transplanted organs. Tacrolimus got its FDA approval in 1994 to be recommended in liver transplantation. Later, its usage has been extended to kidney, heart, lungs and limb transplantation.

Your doctor will decide the dose of this Tacrolimus formulation after evaluating your health condition. Many factors need to be considered, including the age, gender, and bodyweight of the patient. The recommended dose varies from patient to patient. Be sure to take medicine under medical supervision. Administer the tablet consistently with or without food. Do not consume grapefruit or grapefruit juice during the treatment. While you take medicine, you should not receive any live vaccine such as measles, mumps, polio by mouth, rubella, flu vaccines through your nose, chickenpox, typhoid, yellow fever, and TB vaccines.

There is a risk of new-onset diabetes after transplant; therefore, it is important to monitor blood glucose. Do not take the immunosuppressive agent if you are hypersensitive to any ingredients of the medicine. 

Before you take Prograf 1 mg, inform your doctor if you plan to receive any live vaccine., have liver impairment, heart problem, or kidney disease. Your doctor should be aware of your pregnancy status. The immunosuppressive drug may harm your unborn baby, so you must tell your doctor if you are pregnant or plan to become pregnant. Also, if you are breastfeeding or plan to breastfeed, as Tacrolimus can pass into your breast milk. Therefore, it is important to decide with your doctor if you should take this immunosuppressive drug or breastfeed. You should not do both at the same time. Tell your doctor about all the medicines you take, including those you obtained over the counter from a chemist shop, including vitamins and herbal supplements. Especially, inform your doctor if you take sirolimus, cyclosporine, and nelfinavir. Discuss with your doctor if you take any of these medicines. The immunosuppressive drug may affect how other medicines work, or other medicines may affect how Tacrolimus work.

Every medicine, including Pangraf 1 mg, shows some side effects. The drug's common and serious side effects are vomiting, blurred vision, weakness, herpes zoster, lung damage, seizures, confusion, kidney problems, hypertension, dizziness, depression, insomnia, itching, tremors, and cardiac damage. It is important to report the side effects of your medicine. You should give a complete list of prescription or non-prescription medications to inform him/her about any other diseases. This helps your doctor to decide the dose of Pangraf that suits best to you.