Pangraf 0.5mg


US$ 1.10

In stock
Pack Size Qty Price Per Pill or Unit Price Offer
30 Tablet/s US$ 1.10 US$ 33.11
60 Tablet/s US$ 1.10 US$ 66.22
90 Tablet/s US$ 1.10 US$ 99.32



SKU 1044
US Brand Name Prograf
Strength 0.5mg
Generic Name Tacrolimus
Manufacturer Panacea



Tacrolimus is a potent drug discovered from the fermented broth of  Japanese soil sample that is comprised of Streptomyces bacteria. Tacrolimus is an immunosuppressive drug that is given in organ transplantation. It is given in order to avoid rejection of transplanted organs. Organ transplantation is the only treatment opted for end stage organ failure such as liver and heart failure. Physician remove the organ either from a living donor or donor who has died. It is one of the most trusted medicine recommended in organ transplantation. It can be taken alone or can be given along with the other medicines to avoid rejection of any transplanted organs. Tacrolimus got its FDA approval in 1994 to be recommended in liver transplantation. Later on, its usage has been extended to kidney, heart, lungs and limb transplantation.

The ailments, it is used for:

Tacrolimus is an immunosuppressive drug recommended in organ transplantation.

Understanding the drug Tacrolimus:

Tacrolimus is a potent macrolide immunosuppressive drug indicated in organ transplantation.

How it works?

Tacrolimus is a macrolide drug that exhibits the suppressing effect by stopping the activity of an enzyme calcineurin crucial for the activation of immune cells i.e. T cells. Calcineurin has a great role in stimulating the growth and differentiation of the T cell response. T cells have a vital role in cell mediated immunity. This way, by inhibiting the activity of Calcineurin enzyme it suppresses the immune system and avoids rejection of transplanted organs.

 When should you avoid it?

You should not take Tacrolimus if you:

  • Are allergic to Tacrolimus
  • Are allergic to medicines, foods and other substances
  • Are suffering from diabetes
  • Are suffering from hypertension or any heart problems
  • Have a weakened immune system
  • Have kidney problems
  • Have liver disease
  • Are suffering from liver problems
  • Are pregnant or planning to become a pregnant
  • Are breastfeeding

How much to take?

The dose is decided by the physician after evaluating your health condition. Many grounds are considered such as age, gender and body weight. The recommended dose depends varies from patient to patient. Always take the dose as prescribed by the doctor.

What are the strengths available?

Tacrolimus is available in one strength preparations on our website:

  • Pangraf 0.5 mg
  • Pangraf 1 mg
  • Pangraf 5 mg

Who is the manufacturer?

Pangraf is manufactured by Panacea biotech, a big pharmaceutical giant and is available on our website in the pack of 30, 60 and 90 tablets.

How to take?

Tacrolimus is taken exactly as prescribed by your doctor.  Swallow the tablet with a full glass of water. Don’t crush or chew the tablet.

When to take?

The dose intake is prescribed by the doctor, after assessing your condition. Always take the medicine as per the prescription.

For how long should it be taken?

Take the medicine as long as recommended by the Doctor. Always ask the doctor before stopping the drug intake.

What if you take too much (overdose)?

If overdose, immediately consult with your concerned doctor. Take medical help as soon as possible if you encounter any unusual symptoms.

What if you miss the dose?

Try to take the medicine at the same time each day; this reduces the chances of missing a dose. Talk to your Doctor if you miss the dose. Don’t double up the dose in order to compensate with the previous one.

What are the side effects?

Every medicine shows some side effects, same way this drug also has      some undesired effects with it. Tacrolimus shows common and serious side effects such as:

  • Dizziness
  • Vomiting
  • Hypertension
  • Kidney problems
  • Blurred vision
  • Insomnia
  • Confusion
  • Weakness
  • Depression
  • Seizures
  • Herpes zoster
  • Polyoma virus infection
  • Lung damage
  • Seizures
  • Tremors
  • Cardiac damage
  • Itching .

Are there any possible drug interactions?

Always inform your doctor about the drugs you are taking till date. Give a complete list of prescription or non prescription drugs and any other disease conditions. This way, the  doctor is able to decide and give you the list of drugs and other things that may interact with Tacrolimus.

What are the things to be taken care of?

  • Always take the medicine as per the prescription
  • Don’t use the expired drugs
  • Don’t share your medicine with anybody, even if they have the same symptoms
  • It is very important to maintain personal hygiene, avoid coming in contact with an already infected person.
  • Don’t eat grapefruit or drink grapefruit juice while using this medicine
  • Always store the medicine at the room temperature and away from moisture, heat and light
  • If you miss the dose, consult with your doctor
  • Consult with your pharmacist about the proper disposal of the drug
  • Keep a complete record of all the medicines you are taking along with this medicine
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