Nintena 150 is a prescription treatment used for the following conditions:

    — Idiopathic pulmonary fibrosis is when the lungs become scarred, and breathing difficulties occur.

    — A long-lasting interstitial lung disease such as rheumatoid arthritis, in which lung fibrosis (scarring of the tissue) continues to worsen

    — To slow the rate of decline in lung function with a systemic sclerosis-associated interstitial lung disorder (SSc-ILD). Patients suffering from SSc-ILD are characterized by inflammation and progressive scarring of the lungs that can contribute to respiratory failure.

Nintena 150 mg twice daily reduces disease progression in patients with idiopathic pulmonary fibrosis with minimum side effects. Take the capsule two times a day, approximately twelve hours apart, at about the same time each day (one capsule in the morning and one in the evening). Swallow the capsule with water, and do not chew the capsules. It is suggested that you take the capsule with food. You may take them during or immediately before or after a meal. Do not crush or open the capsule. Do not take more than the recommended amount of 100 mg. If you cannot tolerate the recommended dose of 100 mg, you may be advised to discontinue treatment. Do not reduce the dose or stop the treatment without consulting your doctor. 

Do not take Nintena 150 if you are pregnant or have previously suffered an allergic reaction to Nintedanib, soya, peanut, or any of the other ingredients of the medicine.

Speak to your doctor before taking Nintedanib if you have the following:

• Liver problems
• Renal insufficiency or if an increased amount of protein has been detected in your urine
• Bleeding problems
• Taking anti-coagulant medication such as warfarin or heparin to prevent blood clotting
• Heart problems
• Recently had surgery. Nintena may affect the way your wound heal.
• Hypertension (high blood pressure)
• Pulmonary hypertension (a condition of having abnormally high blood pressure in the blood vessels of the lungs)
• Taking pirfenidone may increase the risk of having nausea, vomiting, diarrhoea, and liver problems
• Enlargement and weakening of a blood vessel wall, also known as an aneurysm

Nintedanib can interact with other medicines. Some medicines may increase Nintena 150 and may increase the risk of side effects. These medicines include ketoconazole, cyclosporine, and erythromycin. Other medicines may lower the levels of  Nintedanib and thus may reduce its effectiveness. These are rifampicin, St.John’s wort, phenytoin, carbamazepine.

Very common side effects Nintena 150 mg capsule are vomiting, nausea, pain in the abdomen, headache, rash, bleeding, weight loss, loss of appetite, and abnormal liver results. You may need to pay special attention if you get diarrhoea which may lead to dehydration. To reduce the symptoms, drink plenty of fluids and contact your doctor immediately.