Efavir 200 mg

Efavirenz

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Description

SKU 361
US Brand Name N/A
Strength 200 mg
Generic Name Efavirenz

Efavir is available as capsules for oral administration containing 200 mg of Efavirenz, a non-nucleoside analog reverse transcriptase inhibitor (NNRTI). It is effective only against RNA viruses such as Human Immunodeficiency Virus (HIV). 

Efavir is used with other HIV medicines to treat human immunodeficiency virus (HIV) infection in adults and children above 3 years of age. This drug must not be used alone as it can cause the virus to develop resistance. Therefore, it is combined with two other medicines to treat the condition. The treatment is referred to as highly active antiretroviral therapy (HAART). It is meant to decrease the virus's ability to multiply and prevent the development of any resistance to treatment. HIV affects the immune system by attacking certain immune cells known as CD4+ cells, which typically fight infection. Also, when many CD4+ cells are attacked, this can lead to acquired immune deficiency syndrome (AIDS). The medicine works to reduce the ability of HIV to multiply and spread. It keeps a check on the amount of virus. This leads to an increase in CD4+ cells, which in turn leads to a recovery of the immune system and reduces the risk of disease progression.

Your dosage will depend on several factors, including your body weight and your doctor's recommendations. Make sure to take the tablets for as long as your doctor advises. Do not stop taking medicine without your doctor’s consent, as this can harm your body.

If you miss a dose of the medicine, take it as soon as you remember. However, if it is close to the time for your next dosage, it is best to avoid the missed one. Do not take a double dosage of the medicine.

Avoid the medicine if you are :

   —  Allergic to the ingredients

   —  Pregnant or are you breastfeeding 

   —  Using the medicine as a single treatment 

   —  Suffering from liver problems

   —  Taking other drugs that interact with the medicine.

 

Several medicines interact with Efavirenz. Drugs that cause a serious reaction are cisapride for reflux, antihistamine terfenadine, triazolam for anxiety, ergot derivatives for migraine, the sedative midazolam, and bepridil for angina.

Other antiretrovirals such as amprenavir, ritonavir, indinavir, atazanavir, saquinavir, antibiotic rifampicin, dietary supplement St. John's Wort, and the antiepileptic carbamazepine.
Drugs that are affected by Efavir: the antibiotics clarithromycin and rifabutin, the antifungals itraconazole and voriconazole, cholesterol-lowering statins like atorvastatin and simvastatin, estrogen-containing oral contraceptives, the antiepileptic carbamazepine, methadone for opioid dependence

Some of the common side effects of the medicine include diarrhoea, abdominal pain, vomiting, nausea, dizziness, skin rash and itching, headache, insomnia, fatigue, inability to concentrate, drowsiness, and abnormal dreaming. Talk to your doctor if any of these become troublesome.

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