Danogen 100 mg is used for the treatment of endometriosis-associated symptoms. It may also be used with surgery or as sole hormonal therapy in patients not responding to other treatments. It is also indicated for the symptomatic relief of severe pain and tenderness caused by breast fibrocystic disease. The lining of the uterus is called the endometrium. Part of it is shed during your periods. In endometriosis, endometrium-like tissue is found outside the womb, such as around the womb, ovaries, intestines, and other organs in the pelvis. Normally, this tissue can be shed during your period. Some women with endometriosis develop symptoms such as pelvic pain, painful periods, painful bowel movements, and pain during intercourse.  

When taken for the treatment of endometriosis, Danazol, the active ingredient of the medicine, shrinks the size of the endometrium, which helps to relieve painful symptoms. It usually starts a few weeks after starting Danogen.  

When used for treating fibrocystic breast disease, Danogen relieves pain and tenderness in the breast and causes the nodule to shrink. Pain and tenderness begin to resolve after about one month. Nodules begin to shrink in size after 2 to 3 months of treatment.    

Treatment with Danogen should not be interrupted, avoiding missing doses. The medicine should be started during your period. You must use a non-hormonal method of contraception while taking This medication.

For fibrocystic breast disease, the usual dose is 100 to 400 mg. This is given in two doses a day for six months. After stopping the medicine, if your symptoms reappear, speak to your doctor; you may be able to start treatment again.

Danogen 100 mg should not be used if you are dealing with abnormal vaginal bleeding, breast tumours, liver/kidney/heart problems, porphyria, a tendency to form blood clots, or an androgen-dependent tumour.    

The medication should not be given to patients with known Danazol allergy. Danazol is contraindicated if you take a medicine called simvastatin, which treats high cholesterol. This drug should not be prescribed to diabetic patients as it may cause insulin resistance. It is advisable not to drink any alcoholic beverages while taking this medicine. Danogen may not show its complete effect. Danazol can cause harm to an unborn baby when used by a pregnant woman. Using this medicine to treat endometriosis may increase the risk of ovarian cancer or induce liver tumours.      

Danogen may cause changes in the levels of your body’s hormones. As a result, you may notice side effects such as acne, mild growth of body hair, oedema,  weight gain, and oiliness of the skin or hair. Decrease in breast size, swelling, flushing, vaginal dryness and itching, increased size of the clitoris, mood changes, seizures, vaginal burning, spotting or bleeding, and visual hallucinations. For any unexpected effects while taking danogen, contact your health care provider.