Besix eye drop 0.6% (5ml) is a Besifloxacin ophthalmic suspension prescribed to treat bacterial conjunctivitis caused by susceptible bacterias. Besifloxacin, the active ingredient in medicine, is a fluoroquinolone, one of the first-line agents for treating and preventing bacterial ocular surface infections, including conjunctivitis and blepharitis. Patients suffering from bacterial conjunctivitis often experience redness or inflammation under the eyelid and the eye’s white area. Symptoms of eye infection include eye pain, gritty sensation, foreign body sensation, sensitivity to light, and blurred vision. The ophthalmic agent acts directly in the eye to provide symptomatic relief and prevent the spread of the infection. It works by inhibiting two important bacterial enzymes required for the bacteria to grow and replicate. According to clinical experts, Besix 0.6% destroys the bacteria by blocking its growth and preventing the spread of infection.

Besix eye drop is for topical ophthalmic use only and should not be injected subconjunctivally. For adults and children 12 months and older, instil one drop in the affected eye thrice daily, four to twelve hours apart for seven days. Do not allow the tip of the applicator or the bottle to touch the eye’s surface or surface around the eyes. Shake the bottle before each application. For appropriate administration, tilt the head back and squeeze one drop into the affected eye. You should continue to use this quinolone medicine for a full week, even if your symptoms have improved.

Prolonged usage may result in the overgrowth of non-susceptible organisms, including fungi. In case of superinfection, discontinue use and discuss with your doctor for alternative therapy. Quinolones, including Besifloxacin, have been associated with hypersensitivity reactions; therefore, patients should be advised to discontinue use immediately and contact their doctor at the first sign of a rash or allergic reaction. 

 While using the ophthalmic solution, patients should not wear contact lenses if they have symptoms of bacterial conjunctivitis or during therapy. The safety and effectiveness of the topical medicine in infants below one year of age has not been established.      

The most frequently reported ocular side effects associated with the use of Besix eye drops were conjunctival redness. Other side effects in Besix ophthalmic suspension patients included eye pain, headache eye pain, pruritus, eye irritation, and blurred vision.