Description of the drug
Sitagliptin and Metformin HCL are the active ingredients in Janumet 50+1000 mg. It is an anti hyperglycemic or anti-diabetic drug that contains DPP-4 inhibitors and is administered orally to help reduce the blood sugar level.
Indications and Usage
Sitagliptin works as an effective medicine to manage diabetes by controlling the level of sugar in the body. It is generally recommended by doctors to treat type 2 diabetes mellitus either alone or in combination with other medicines. It is not advised to treat type 1 diabetes.
Dosage and Administration
1. Recommended dose:
The initial dosage for adults is 100 mg once daily. The dosage of the drug varies from one person to another. It is best to follow the doctor's advice regarding the right dosage. Do not take the medicine without your doctor's recommendation.
2. Method of Administration:
Swallow the tablet with a glass of water. It should be combined with meals for the best results. Make sure to take a balanced diet while taking the medicine. It is important to take the drug at the same time every day. This will ensure that you do not forget to take the medicine. Remember to take the medicine for as long as has been prescribed by your doctor. Keep in mind the medicine helps to control diabetes, but does not cure it.
3. Missed dose:
In case you miss to take a dose, skip the missed dose and take the next dosage at the scheduled time. Do not take two doses to make up for the missed one.
An overdose of the medicine may lead to harmful side effects, which may lead to hypoglycemia. If this is the case, you may need urgent medical help. Consult your doctor immediately if you face any of the symptoms:
Back, muscle or joint pain
Forms and Strengths
• Form: Tablet
• Strengths: Januvia-25 mg, Januvia 50 mg, Januvia 100 mg, Janumet 50+1000 mg, and Janumet 50+500 mg. You can buy Janumet-50+1000 mg online at a much lower price.
Stay away from the medicine if:
• You have an allergy to Sitagliptin or other ingredients in the product
• You are pregnant or planning to have a baby
• You are breastfeeding
• You have kidney problems
• You have infections
• You have pancreatitis
Let your doctor know about your exact medical condition and medical history. Even if you plan to purchase Janumet-50+1000 mg, first speak to your doctor.
Warnings and precautions
Lactic acidosis is a serious metabolic complication that can happen as a result of metformin accumulation while treating with Janumet. Consult your doctor before you start taking the medicine and discuss the risk factors to ensure that you are safe from the side effects.
Some of the side effects of the medicine include:
Soreness in the back of the nose
Low blood sugar
Fast heart rate
Headache and drowsiness
Unusual bleeding or bruising
Dizziness and trouble concentrating
If you experience any of the symptoms, you must get immediate medical help. Inform your doctor immediately if you notice any of the symptoms.
The drug is associated with weight loss. Therefore, remember to ask your doctor if you can take diabetes and cholesterol medicines along with it. Make sure to ask your doctor about the following drugs:
Non-steroidal anti-inflammatory drugs
Aspirin or other salicylates
Monoamine oxidase inhibitors
Before you take the drugs, make sure to ask your doctor about the drugs to avoid as well as the drugs you are presently taking.
Janumet contains the two active ingredients Sitagliptin and Metformin HCL. Sitagliptin works by reducing the high blood glucose. These drugs increase the secretion of insulin and decrease the release of glucagon by the pancreas. This keeps the blood glucose levels at normal levels. When the blood glucose levels become normal, the increased changes in the glucagon and insulin stops and this prevents the hypoglycemic situation.
Metformin Hcl is an antihyperglycemic agent which decreases the glucose production from the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing the glucose uptake and utilization.
Store the medicine in a cool and dry place. Keep it out of the reach of pets and children. Also, keep it away from heat and humidity. Never use medicines that have crossed the expiry date.
It is manufactured by Merck Sharp, international manufacturer and distributor of pharmaceuticals.