Description of the drug

The drug Cipril H is a combination of two active metabolites namely Lisinopril and Hydrochlorothiazide. Lisinopril is an active metabolite which is used in the treatment of high blood pressure, cardiovascular disorders, renal problems, and diabetic symptoms. This drug inhibits the potential working of angiotensin converting enzyme. Hydrochlorothiazide is diuretic water pill that helps in the formation of more urine and helps the body to drain out the extra water and salt.

Indications and Usage

This drug is prescribed to control the serious problems like high blood pressure, hypertension, heart disorders, strokes, and heart attack. Lisinopril+hydrochlorothiazide are the angiotensin converting enzyme and diuretics respectively and effective in treating high blood pressure.. It helps to controls several other medical complications heart attack, strokes, fluctuating blood sugar levels, kidney failure, and renal impairment.

Dosage and administration

1. Recommended dose:

The recommended dose of Lisinoril+Hydrochlorothiazide for adults is 5+12.5 mg once per day. The dose should be adjusted as per the response of the patient towards the drug under the supervision of your doctor. Report your doctor after a regular time interval of 3 to 4 weeks.

2. Mode of administration:

Lisinopril+hydrochlorothiazide is available in the form of a tablet and this makes it easier to be consumed orally with sufficient amount of water. Completely swallow this medicine with water. Do not chew it.

3. Missed dose:

If you forget to take your medication, do take it as soon as you remember it. In the case of any complications please contact your doctor immediately.

4. Overdose:

In case if you take an extra dose, consult your doctor and do as instructed.

Forms and strengths

Lisinoril+hydrochlorothiazide is available in the form of a tablet and is applicable to the following strengths:

 Cipril-H 5+12.5 mg

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Contraindications

Lisinopril+hydrochlorothiazide drug is reported to contraindicate in the following cases:

 Allergic reactions
 Angioedema
 Patients who are sensitive to other angiotensin converting enzyme inhibitors

Warnings and Precautions

 You should give all the relevant information related to your medical background to the doctor. has been reported to cause severe hypersensitive reactions in some cases

 Please consult your doctor before taking Lisinopril+hydrochlorothiazide tablets along with other medications. This may lead to allergic reactions and other severe complications

 In a case of patient has to undergo surgery make sure to inform your doctor beforehand. Anaesthesia can cause hypotension and interfere with the working of this drug.

 Avoid consuming Lisinopril+hydrochlorothiazide before taking any laboratory tests. Lisinopril+hydrochlorothiazide contains hydrochlorothiazide constituent that can decrease the serum plasma levels.

 In case, you have renal disorders or if you are diabetic please, do inform your doctor before consuming this medicine. Lisinopril+hydrochlorothiazide can have an adverse effect on kidneys and heart.

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Side effects

Lisinopril+hydrochlorothiazide is known to have severe complications and some of the below-mentioned side effects:

 Dizziness
 Frequent chills
 Body pain
 Skin problems
 Skin edema
 Diarrhoea or constipation
 Nausea
 Fever
 Breathing difficulties
 Weight gain or weight loss
 Loss of appetite
 Allergic outburst
 Headache
 Cough and cold

Drug interactions

Lisinopril is reported to interact with the following drugs:

 Everolimus – can increase the chances of infection
 Sirolimus - can increase the chances of infection
 Lithium – can increase the level of potassium in blood
 Losartan/valsartan - can increase the level of potassium in blood
 Birth control pills - can increase the level of potassium in blood
 NSAIDs (ibuprofen, naproxen) – can worsen the problems of high blood pressure and heart attack
These drugs, when consumed along with Lisinopril, can cause enhanced side effects and weaken your immune system.

Ingredients

This drug is composed of following two active ingredients:

 Lisinopril 5 mg
 Hydrochlorothiazide 12.5 mg

This drug is a combination of angiotensin converting enzyme inhibitor and thiazide water pill that causes the blood vessels to widen up by flushing out extra fluid from the body. This drug blocks the functioning of angiotensin converting enzyme which is essential in maintaining the blood pressure. Low levels of this enzyme cause a decreased conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor and helps in secretion of aldosterone in the body.

Storage

 Store this drug under room temperature and away from heat and moisture
 Keep the medicine away from the reach of pets and children
 Do not refrigerate the medicine

Manufacturer

Lisinoril+Hydrochlorothiazide drug is manufactured by one of the leading multinational pharmaceutical Indian company, Cipla. This Indian based company is one of the top biotechnology giants that uses innovative technologies for various drug discovery programs.